[HTML][HTML] The bidirectional relationship between periodontal disease and diabetes mellitus—A review

I Păunică, M Giurgiu, AS Dumitriu, S Păunică… - Diagnostics, 2023 - mdpi.com
Periodontitis is a chronic inflammatory disease caused by the presence of a bacterial biofilm
known as dental plaque. This biofilm affects the supporting apparatus of the teeth, especially …

[HTML][HTML] The pathogenesis of diabetes

H Guo, H Wu, Z Li - International journal of molecular sciences, 2023 - mdpi.com
Diabetes is the most common metabolic disorder, with an extremely serious effect on health
systems worldwide. It has become a severe, chronic, non-communicable disease after …

Impaired lipophagy induced-microglial lipid droplets accumulation contributes to the buildup of TREM1 in diabetes-associated cognitive impairment

Q Li, Y Zhao, H Guo, Q Li, C Yan, Y Li, S He, N Wang… - Autophagy, 2023 - Taylor & Francis
Neuroinflammation caused by microglial activation and consequent neurological impairment
are prominent features of diabetes-associated cognitive impairment (DACI). Microglial …

Synthesis, biological evaluation and molecular modelling of 3-Formyl-6-isopropylchromone derived thiosemicarbazones as α-glucosidase inhibitors

R Basri, S Ullah, A Khan, SN Mali, O Abchir, S Chtita… - Bioorganic …, 2023 - Elsevier
Abstract Type-2 Diabetes Mellitus (T2DM) is one of the most common metabolic disorders in
the world and over the past three decades its incidence has increased drastically. α …

The neuroprotective and antidiabetic effects of trigonelline: A review of signaling pathways and molecular mechanisms

Y Liang, X Dai, Y Cao, X Wang, J Lu, L Xie, K Liu, X Li - Biochimie, 2023 - Elsevier
The global epidemic of diabetes has brought heavy pressure on public health. New effective
anti-diabetes strategies are urgently needed. Trigonelline is the main component of …

[HTML][HTML] Assessment of anticancer, antimicrobial, antidiabetic, anti-obesity and antioxidant activity of Ocimum Basilicum seeds essential oil from Palestine

AM Eid, N Jaradat, N Shraim, M Hawash, L Issa… - … Medicine and Therapies, 2023 - Springer
Background Many modern pharmaceutical researchers continue to focus on the discovery
and evaluation of natural compounds for possible therapies for obesity, diabetes, infections …

[HTML][HTML] Nitrotyrosine, nitrated lipoproteins, and cardiovascular dysfunction in patients with type 2 diabetes: What do we know and what remains to be explained?

GK Jakubiak, G Cieślar, A Stanek - Antioxidants, 2022 - mdpi.com
Diabetes mellitus (DM) is a strong risk factor for the development of cardiovascular diseases
(CVDs), which are the most important cause of morbidity and mortality in the population of …

[HTML][HTML] New insights and potential therapeutic interventions in metabolic diseases

VJ Clemente-Suárez, A Martín-Rodríguez… - International Journal of …, 2023 - mdpi.com
Endocrine homeostasis and metabolic diseases have been the subject of extensive
research in recent years. The development of new techniques and insights has led to a …

Preparation, structural properties, and in vitro and in vivo activities of peptides against dipeptidyl peptidase IV (DPP-IV) and α-glucosidase: a general review

X Mu, R Wang, C Cheng, Y Ma, Y Zhang… - Critical Reviews in Food …, 2023 - Taylor & Francis
Diabetes is one of the fastest-growing and most widespread diseases worldwide.
Approximately 90% of diabetic patients have type 2 diabetes. In 2019, there were about 463 …

Type 2 diabetes mellitus and efficacy outcomes from immune checkpoint blockade in patients with cancer

A Cortellini, A D'Alessio, S Cleary, S Buti… - Clinical Cancer …, 2023 - AACR
Purpose: No evidence exists as to whether type 2 diabetes mellitus (T2DM) impairs clinical
outcome from immune checkpoint inhibitors (ICI) in patients with solid tumors. Experimental …