Biosynthesis of milk fat, protein, and lactose: roles of transcriptional and posttranscriptional regulation

JS Osorio, J Lohakare, M Bionaz - Physiological genomics, 2016 - journals.physiology.org
The demand for high-quality milk is increasing worldwide. The efficiency of milk synthesis
can be improved by taking advantage of the accumulated knowledge of the transcriptional …

Nutritional and physiologic significance of α-lactalbumin in infants

B Lönnerdal, EL Lien - Nutrition Reviews, 2003 - academic.oup.com
Abstract α-Lactalbumin is the major protein in breast milk (20-25% of total protein) and has
been described to have several physiologic functions in the neonatal period. In the …

A novel dynamic impact approach (DIA) for functional analysis of time-course omics studies: validation using the bovine mammary transcriptome

M Bionaz, K Periasamy, SL Rodriguez-Zas, WL Hurley… - PloS one, 2012 - journals.plos.org
The overrepresented approach (ORA) is the most widely-accepted method for functional
analysis of microarray datasets. The ORA is computationally-efficient and robust; however, it …

GWA Analysis for Milk Production Traits in Dairy Sheep and Genetic Support for a QTN Influencing Milk Protein Percentage in the LALBA Gene

E García-Gámez, B Gutierrez-Gil, G Sahana… - 2012 - journals.plos.org
In this study, we used the Illumina OvineSNP50 BeadChip to conduct a genome-wide
association (GWA) analysis for milk production traits in dairy sheep by analyzing a …

[HTML][HTML] Growth hormone can induce expression of four major milk protein genes in transfected MAC-T cells

Y Zhou, RM Akers, H Jiang - Journal of dairy science, 2008 - Elsevier
Growth hormone (GH) can increase milk production in cattle, and this effect was thought to
be mediated by an indirect mechanism because traditional ligand binding assays failed to …

[HTML][HTML] Expression and characterization of bioactive recombinant human α-lactalbumin in the milk of transgenic cloned cows

J Wang, P Yang, B Tang, X Sun, R Zhang, C Guo… - Journal of dairy …, 2008 - Elsevier
Improvement of the nutritional value of cow milk with transgenic expression of recombinant
human α-lactalbumin (α-LA) has been previously attempted. However, the detailed …

Serotonin: a local regulator in the mammary gland epithelium

ND Horseman, RJ Collier - Annu. Rev. Anim. Biosci., 2014 - annualreviews.org
Serotonin (5-hydroxytryptamine, 5-HT) is a very simple molecule that plays key roles in
complex communication mechanisms within the animal body. In the mammary glands …

Lactose Synthase Components in Milk: Concentrations of α‐Lactalbumin and β1, 4‐Galactosyltransferase in Milk of Cows from Several Breeds at Various Stages of …

GT Bleck, MB Wheeler, LB Hansen… - … in domestic animals, 2009 - Wiley Online Library
Contents It is believed that milk production is determined by the number and activity of
mammary secretory cells. Secretory activity, as assessed by milk volume, depends on …

High-protein diet during gestation and lactation affects mammary gland mRNA abundance, milk composition and pre-weaning litter growth in mice

M Kucia, M Langhammer, S Görs, E Albrecht… - Animal, 2011 - Elsevier
We evaluated the effect of a high-protein diet (HP) on pregnancy, lactational and rearing
success in mice. At the time of mating, females were randomly assigned to isoenergetic diets …

[图书][B] Alpha-lactalbumin

EA Permi͡akov - 2005 - books.google.com
Small acidic protein a-lactalbumin, one of the major protein components of milk, is one of the
most extensively investigated Ca2+-binding proteins, which does not belong to the EF-hand …