Dendrimers are novel polymeric nanoarchitectures characterized by hyper-branched 3D-
structure having multiple functional groups on the surface that increases their functionality …

A bird's eye view is now demanded in the area of cancer research to suppress the suffering
of cancer patient and mediate the lack of treatment related to chemotherapy. Chemotherapy …

Triple-negative breast cancer (TNBC) is one major type of cancer for which there has been
no effective therapy to date. An important reason for it being the lack of expression of …

1. DENDRIMERS AND GENE DELIVERY Gene therapy represents a promising option for
the treatment of diseases such as inherited disorders, viral infections, and cancers. 1− 3 A …

Highlights•Dendrimers are nanovectors with well-defined architecture and tunable surface
characteristics.•Dendrimers can take advantage of passive and active tumor targeting for …

Therapeutics based on RNA interference mechanisms are highly promising for the
management of several diseases including multi-drug resistant cancers. However, effective …

Small interfering RNA (siRNA) is emerging as a novel therapeutic for treating various
diseases, provided a safe and efficient delivery is available. In particular, specific delivery to …

Conspectus Dendrimers, notable for their well-defined radial structures with numerous
terminal functionalities, hold great promise for biomedical applications such as drug …

Dendrimers have attracted immense interest in science and technology due to their unique
chemical structure that offers a myriad of opportunities for researchers. Dendritic design …

The research of integrin-targeted anticancer agents has recorded important advancements
in ingenious design of delivery systems, based either on the prodrug approach, or on …