Hormetic Nutrition and Redox Regulation in Gut–Brain Axis Disorders

M Scuto, F Rampulla, GM Reali, SM Spanò… - Antioxidants, 2024 - mdpi.com
The antioxidant and anti-inflammatory effects of hormetic nutrition for enhancing stress
resilience and overall human health have received much attention. Recently, the gut–brain …

Gastrointestinal hormone-mediated beneficial bioactivities of bitter polyphenols

N Osakabe, M Ohmoto, T Shimizu, N Iida, T Fushimi… - Food Bioscience, 2024 - Elsevier
Recently, there has been a notable emphasis on the homeostatic regulation by taste
receptors expressed in the extra-oral gastrointestinal (GI) tract. Type 2 taste receptors (T2R) …

Investigating hormesis, aging, and neurodegeneration: From bench to clinics

V Calabrese, U Wenzel, T Piccoli, UM Jacob… - Open …, 2024 - degruyter.com
Mitochondria-derived reactive oxygen species production at a moderate physiological level
plays a fundamental role in the anti-aging signaling, due to their action as redox-active …

Sensory Properties, Redox Characteristics, and Impact on the Hemodynamics of the Flavanol-Rich Fraction Originated Grape and Blueberry

N Osakabe, T Shoji, K Onishi, C Hirahata, K Hiroki… - 2024 - preprints.org
Several epidemiological studies and intervention trials have demonstrated that flavanols
present in grapes and blueberries can lower the risk of cardiovascular disease. However …