[HTML][HTML] Adipose tissue distribution, inflammation and its metabolic consequences, including diabetes and cardiovascular disease

A Chait, LJ Den Hartigh - Frontiers in cardiovascular medicine, 2020 - frontiersin.org
Adipose tissue plays essential roles in maintaining lipid and glucose homeostasis. To date
several types of adipose tissue have been identified, namely white, brown, and beige, that …

Adipose tissue-liver cross talk in the control of whole-body metabolism: implications in nonalcoholic fatty liver disease

V Azzu, M Vacca, S Virtue, M Allison, A Vidal-Puig - Gastroenterology, 2020 - Elsevier
Adipose tissue and the liver play significant roles in the regulation of whole-body energy
homeostasis, but they have not evolved to cope with the continuous, chronic, nutrient …

Long non-coding RNAs in regulation of adipogenesis and adipose tissue function

T Squillaro, G Peluso, U Galderisi, G Di Bernardo - Elife, 2020 - elifesciences.org
Complex interaction between genetics, epigenetics, environment, and nutrition affect the
physiological activities of adipose tissues and their dysfunctions, which lead to several …

Multifactorial basis and therapeutic strategies in metabolism-related diseases

JVS Guerra, MMG Dias, AJVC Brilhante, MF Terra… - Nutrients, 2021 - mdpi.com
Throughout the 20th and 21st centuries, the incidence of non-communicable diseases
(NCDs), also known as chronic diseases, has been increasing worldwide. Changes in …

The impact of the adipose organ plasticity on inflammation and cancer progression

LH Corrêa, GS Heyn, KG Magalhaes - Cells, 2019 - mdpi.com
Obesity is characterized by chronic and low-grade systemic inflammation, an increase of
adipose tissue, hypertrophy, and hyperplasia of adipocytes. Adipose tissues can be …

[HTML][HTML] β3-Adrenergic receptors regulate human brown/beige adipocyte lipolysis and thermogenesis

C Cero, HJ Lea, KY Zhu, F Shamsi, YH Tseng… - JCI insight, 2021 - ncbi.nlm.nih.gov
Abstract β 3-Adrenergic receptors (β 3-ARs) are the predominant regulators of rodent brown
adipose tissue (BAT) thermogenesis. However, in humans, the physiological relevance of …

Anti-obesity effects of dietary calcium: the evidence and possible mechanisms

F Zhang, J Ye, X Zhu, L Wang, P Gao, G Shu… - International journal of …, 2019 - mdpi.com
Obesity is a serious health challenge worldwide and is associated with various
comorbidities, including dyslipidemia, type 2 diabetes, and cardiovascular disease …

Browning of adipocytes: A potential therapeutic approach to obesity

V Schirinzi, C Poli, C Berteotti, A Leone - Nutrients, 2023 - mdpi.com
The increasing prevalence of overweight and obesity suggests that current strategies based
on diet, exercise, and pharmacological knowledge are not sufficient to tackle this epidemic …

Adipocyte browning and resistance to obesity in mice is induced by expression of ATF3

CF Cheng, HC Ku, JJ Cheng, SW Chao, HF Li… - Communications …, 2019 - nature.com
Billions of people have obesity-related metabolic syndromes such as diabetes and
hyperlipidemia. Promoting the browning of white adipose tissue has been suggested as a …

The protective effects of sulforaphane on high-fat diet-induced obesity in mice through browning of white fat

Y Liu, X Fu, Z Chen, T Luo, C Zhu, Y Ji… - Frontiers in …, 2021 - frontiersin.org
Background: Sulforaphane (SFN), an isothiocyanate naturally occurring in cruciferous
vegetables, is a potent indirect antioxidant and a promising agent for the control of metabolic …