Although the conventional activities of p53 such as cell cycle arrest, senescence, and
apoptosis are well accepted as the major checkpoints in stress responses, accumulating …

Ferroptosis is an iron-dependent form of regulated cell death with distinct characteristics,
including altered iron homeostasis, reduced defense against oxidative stress, and abnormal …

Neutrophil extracellular traps (NETs) production is a major strategy employed by
polymorphonuclear neutrophils (PMNs) to fight against microbes. NETs have been …

Itaconate, a metabolite produced during inflammatory macrophage activation, has been
extensively described to be involved in immunoregulation, oxidative stress, and lipid …

Background Sepsis is a fatal disease with a high rate of morbidity and mortality, during
which acute lung injury is the earliest and most serious complication. Injury of pulmonary …

Drugs, viruses, and chemical poisons stimulating live in a short period of time can cause
acute liver injury (ALI). ALI can further develop into serious liver diseases such as cirrhosis …

Abstract Rationale Circular RNAs (circRNAs) have been demonstrated to contribute to
esophageal cancer progression. CircBCAR3 (hsa_circ_0007624) is predicted to be …

Ischemia‐reperfusion (I/R) is a pathological process that occurs in many organs and
diseases. Reperfusion, recovery of blood flow, and reoxygenation often lead to reperfusion …

Ferroptosis, a unique type of cell death, is characterized by iron-dependent accumulation
and lipid peroxidation. It is closely related to multiple biological processes, including iron …

Introduction Inflammation is a defensive response of the organism to irritation which is
manifested by redness, swelling, heat, pain and dysfunction. The inflammatory response …