Cracking the intestinal lymphatic system window utilizing oral delivery vehicles for precise therapy

YB Miao, T Xu, Y Gong, A Chen, L Zou, T Jiang… - Journal of …, 2023 - Springer
Oral administration is preferred over other drug delivery methods due to its safety, high
patient compliance, ease of ingestion without discomfort, and tolerance of a wide range of …

Spray-Dried Nanolipid Powders for Pulmonary Drug Delivery: A Comprehensive Mini Review

MH Abu Elella, AO Al Khatib, H Al-Obaidi - Pharmaceutics, 2024 - mdpi.com
Lung diseases have received great attention in the past years because they contribute
approximately one-third of the total global mortality. Pulmonary drug delivery is regarded as …

Enhanced Codelivery of Gefitinib and Azacitidine for Treatment of Metastatic-Resistant Lung Cancer Using Biodegradable Lipid Nanoparticles

EM Elzayat, AY Sherif, FA Nasr, MW Attwa, DH Alshora… - Materials, 2023 - mdpi.com
Lung cancer is a formidable challenge in clinical practice owing to its metastatic nature and
resistance to conventional treatments. The codelivery of anticancer agents offers a potential …

Assembly of nanostructured lipid carriers loaded gefitinib and simvastatin as hybrid therapy for metastatic breast cancer: Codelivery and repurposing approach

AY Sherif, GI Harisa, AA Shahba… - Drug Development …, 2023 - Wiley Online Library
Breast cancer represents a life‐threatening problem globally. The major challenge in the
clinical setting is the management of cancer resistance and metastasis. Hybrid therapy can …

Chitosan-enclosed SLN improved SV-induced hepatocellular cell carcinoma death by modulation of IQGAP gene expression, JNK, and HDAC activities

GI Harisa, AH Bakheit, S Alshehri, SM Attia… - Molecular Biology …, 2024 - Springer
Background Hepatocellular carcinoma (HCC) is a global life-threatening problem and
therapeutic interventions are still encountered. IQGAP genes are involved in HCC …

Challenges and Limitations of the Lymphatic Drug Delivery Systems

Z Khademi, N Mottaghi-Dastjerdi, H Morad… - Advanced Targeting of …, 2024 - Springer
The lymphatic system, the secondary vascular system in mammals, comprises lymph,
vessels, nodes, and associated organs, playing vital roles in circulatory and immune …

Physicochemical Properties of Carriers for Targeting Lymphatic System

CE Umeyor, P Kumbhar, R Trivedi, P Kolekar… - Advanced Targeting of …, 2024 - Springer
The lymphatic biology plays pivotal roles in human health due to overwhelming impacts of
the lymphatic processes, mechanisms, regulations, and functions. It is, therefore, evidently …

Transdermal Application of Nanoparticles for Targeting Lymphatic System

D Kulkarni, P Panzade, V Bodhankar… - Advanced Targeting of …, 2024 - Springer
Transdermal route of administration provides a versatile and efficient approach for the
delivery of various drug categories. Transdermal drug delivery through nanocarriers …

Polymer-Based Carriers for Targeting Lymphatic System

A Dubey, A Shetty, M Mahadev, P Jain - Advanced Targeting of the …, 2024 - Springer
The lymphatic system is a crucial part of the immune system, responsible for surveillance
and response to immune challenges. It is a parallel vascular network that lacks a central …

Metal-Based Carriers for Targeting Lymphatic System

V Patel, G Arde, G Kashid, JK Patel, N Dhas - Advanced Targeting of the …, 2024 - Springer
Lymphatic drug delivery systems play a crucial role in enhancing mucosal immunity and
chemotherapy efficacy and facilitating oral absorption. Despite the intricate nature of the …