Neuroprotective effect of SGLT2 inhibitors
A Pawlos, M Broncel, E Woźniak, P Gorzelak-Pabiś - Molecules, 2021 - mdpi.com
Patients with diabetes are at higher risk of cardiovascular diseases and cognitive
impairment. SGLT2 inhibitors (Empagliflozin, Canagliflozin, Dapagliflozin, Ertugliflozin …
impairment. SGLT2 inhibitors (Empagliflozin, Canagliflozin, Dapagliflozin, Ertugliflozin …
[HTML][HTML] Pathophysiology of blood brain barrier dysfunction during chronic cerebral hypoperfusion in vascular cognitive impairment
The prevalence of cerebrovascular disease increases with age, placing the elderly at a
greater lifetime risk for dementia. Vascular cognitive impairment (VCI) encompasses a …
greater lifetime risk for dementia. Vascular cognitive impairment (VCI) encompasses a …
Oxidative stress and beta amyloid in Alzheimer's disease. Which comes first: the chicken or the egg?
The pathogenesis of Alzheimer's disease involves β amyloid (Aβ) accumulation known to
induce synaptic dysfunction and neurodegeneration. The brain's vulnerability to oxidative …
induce synaptic dysfunction and neurodegeneration. The brain's vulnerability to oxidative …
Metal ions in Alzheimer's disease: a key role or not?
Y Liu, M Nguyen, A Robert… - Accounts of chemical …, 2019 - ACS Publications
Conspectus Despite tremendous research efforts in universities and pharmaceutical
companies, effective drugs are still lacking for the treatment of Alzheimer's disease (AD). The …
companies, effective drugs are still lacking for the treatment of Alzheimer's disease (AD). The …
Statins use in Alzheimer disease: bane or boon from frantic search and narrative review
Alzheimer's disease (AD) was used to describe pre-senile dementia to differentiate it from
senile dementia, which develops in the adult age group of more than 65 years. AD is …
senile dementia, which develops in the adult age group of more than 65 years. AD is …
The neurovascular unit dysfunction in Alzheimer's disease
LO Soto-Rojas, M Pacheco-Herrero… - International Journal of …, 2021 - mdpi.com
Alzheimer's disease (AD) is the most common neurodegenerative disease worldwide.
Histopathologically, AD presents with two hallmarks: neurofibrillary tangles (NFTs), and …
Histopathologically, AD presents with two hallmarks: neurofibrillary tangles (NFTs), and …
Chronic cerebral hypoperfusion: a critical feature in unravelling the etiology of vascular cognitive impairment
Vascular cognitive impairment (VCI) describes a wide spectrum of cognitive deficits related
to cerebrovascular diseases. Although the loss of blood flow to cortical regions critically …
to cerebrovascular diseases. Although the loss of blood flow to cortical regions critically …
Neutrophil counts and cardiovascular disease
J Luo, JQ Thomassen, BG Nordestgaard… - European Heart …, 2023 - academic.oup.com
Abstract Background and Aims Anti-inflammatory trials have shown considerable benefits for
cardiovascular disease. High neutrophil counts, an easily accessible inflammation …
cardiovascular disease. High neutrophil counts, an easily accessible inflammation …
Vascular dementia and underlying sex differences
Vascular dementia (VaD) is the second most common form of dementia after Alzheimer's
disease (AD); where Alzheimer's accounts for 60–70% of cases of dementia and VaD …
disease (AD); where Alzheimer's accounts for 60–70% of cases of dementia and VaD …
Interactions between glial cells and the blood-brain barrier and their role in Alzheimer's disease
M Zhao, XF Jiang, HQ Zhang, JH Sun, H Pei… - Ageing research …, 2021 - Elsevier
Abstract Alzheimer's disease (AD), which is an irreversible neurodegenerative disorder
characterized by senile plaques and neurofibrillary tangles, is the most common form of …
characterized by senile plaques and neurofibrillary tangles, is the most common form of …