Dietary phenolic compounds as promising therapeutic agents for diabetes and its complications: A comprehensive review
D Aryal, S Joshi, NK Thapa, P Chaudhary… - Food Science & …, 2024 - Wiley Online Library
In the middle of an ever‐changing landscape of diabetes care, precision medicine, and
lifestyle therapies are becoming increasingly important. Dietary polyphenols are like hidden …
lifestyle therapies are becoming increasingly important. Dietary polyphenols are like hidden …
Essential moieties of myricetins, quercetins and catechins for binding and inhibitory activity against α-Glucosidase
Abstract α-Glucosidase inhibition of 11 flavonoids, including myricetins, quercetins and
catechins were studied through initial reaction velocity, IC 50 value, inhibition kinetics …
catechins were studied through initial reaction velocity, IC 50 value, inhibition kinetics …
Soluble dietary fibres decrease α-glucosidase inhibition of epigallocatechin gallate through affecting polyphenol-enzyme binding interactions
J Li, J Zhang, W Yu, H Gao, IMY Szeto, H Feng, X Liu… - Food Chemistry, 2023 - Elsevier
The effects of soluble dietary fibres (SDFs) on α-glucosidase inhibition of EGCG were
studied. Three arabinoxylans and polygalacturonic acid (PGA) significantly decreased …
studied. Three arabinoxylans and polygalacturonic acid (PGA) significantly decreased …
Lowering glycemic levels via gastrointestinal tract factors: the roles of dietary fiber, polyphenols, and their combination
F Li, K Zeng, J Ming - Critical Reviews in Food Science and …, 2023 - Taylor & Francis
Dietary fiber (DF) and polyphenols (DP) are typical blood sugar-lowering components, and
both play distinct yet interconnected roles in exerting their blood sugar-lowering effects. We …
both play distinct yet interconnected roles in exerting their blood sugar-lowering effects. We …
Gallate moiety of catechin Is essential for inhibiting CCL2 chemokine-mediated monocyte recruitment
Leukocyte recruitment witnesses an orchestrated complex formation between the
chemokines and their molecular partners. CCL2 chemokine that regulates monocyte …
chemokines and their molecular partners. CCL2 chemokine that regulates monocyte …
Thermally Induced Covalent Cross-Linking of Proanthocyanidins and Pectin in Processed Fruit-Based Foods
Q Li, Y Cao, H Lin, T Zhao… - Journal of Agricultural …, 2023 - ACS Publications
The covalent interactions between proanthocyanidins (PAs) and pectin during thermal
processing was investigated. An acid–butanol assay clearly showed that PAs were …
processing was investigated. An acid–butanol assay clearly showed that PAs were …
Exploration of the inhibitory mechanisms of trans-polydatin/resveratrol on α-glucosidase by multi-spectroscopic analysis, in silico docking and molecular dynamics …
R Wang, R Fan, T Meng, L Wang - … Acta Part A: Molecular and Biomolecular …, 2023 - Elsevier
Plant-derived phenolics as natural α-glucosidase (α-GLU) inhibitors have attached great
attention in the treatment of type-II diabetes mellitus currently. In this study, trans-polydatin …
attention in the treatment of type-II diabetes mellitus currently. In this study, trans-polydatin …
Inconsistency between polyphenol-enzyme binding interactions and enzyme inhibition: Galloyl moiety decreases amyloglucosidase inhibition of catechins
J Zhang, S Li, X Liu, L Sun - Food Research International, 2023 - Elsevier
Inhibiting carbohydrate-hydrolyzing enzymes has been considered as an effective approach
for controlling starch digestion and postprandial blood glucose level. α-Amylase and …
for controlling starch digestion and postprandial blood glucose level. α-Amylase and …
[HTML][HTML] Water Caltrop (Trapa quadrispinosa Roxb.) Husk Improves Oxidative Stress and Postprandial Blood Glucose in Diabetes: Phenolic Profiles, Antioxidant …
Y Zhang, S Cai, S Ma, S Zhao, J Yi, L Zhou - Antioxidants, 2022 - mdpi.com
The aim of this study was to investigate the phenolic profiles, antioxidant activities and α-
glycosidase inhibitory activities of three different phenolic fractions from water caltrop (Trapa …
glycosidase inhibitory activities of three different phenolic fractions from water caltrop (Trapa …
Enzymic catalyzing affinity to substrate affects inhibitor-enzyme binding interactions: Inhibition behaviors of EGCG against starch digestion by individual and co …
S Zhu, J Li, W Li, S Li, X Yang, X Liu, L Sun - Food Chemistry, 2022 - Elsevier
Abstract The inhibition of (-)-epigallocatechin-gallate (EGCG) against starch digestion by α-
amylase (AA), amyloglucosidase (AMG) and co-existing enzymes (AA/AMG) were …
amylase (AA), amyloglucosidase (AMG) and co-existing enzymes (AA/AMG) were …