[HTML][HTML] Antimicrobial peptides for combating drug-resistant bacterial infections
J Xuan, W Feng, J Wang, R Wang, B Zhang, L Bo… - Drug Resistance …, 2023 - Elsevier
The problem of drug resistance due to long-term use of antibiotics has been a concern for
years. As this problem grows worse, infections caused by multiple bacteria are expanding …
years. As this problem grows worse, infections caused by multiple bacteria are expanding …
Metal organic framework-based antibacterial agents and their underlying mechanisms
D Han, X Liu, S Wu - Chemical Society Reviews, 2022 - pubs.rsc.org
Bacteria, as the most abundant living organisms, have always been a threat to human life
until the development of antibiotics. However, with the wide use of antibiotics over a long …
until the development of antibiotics. However, with the wide use of antibiotics over a long …
Biomaterial-based antimicrobial therapies for the treatment of bacterial infections
PP Kalelkar, M Riddick, AJ García - Nature Reviews Materials, 2022 - nature.com
The rise in antibiotic-resistant bacteria, including strains that are resistant to last-resort
antibiotics, and the limited ability of antibiotics to eradicate biofilms have necessitated the …
antibiotics, and the limited ability of antibiotics to eradicate biofilms have necessitated the …
The multifaceted nature of antimicrobial peptides: Current synthetic chemistry approaches and future directions
BH Gan, J Gaynord, SM Rowe, T Deingruber… - Chemical Society …, 2021 - pubs.rsc.org
Bacterial infections caused by 'superbugs' are increasing globally, and conventional
antibiotics are becoming less effective against these bacteria, such that we risk entering a …
antibiotics are becoming less effective against these bacteria, such that we risk entering a …
Antimicrobial peptides: an update on classifications and databases
Antimicrobial peptides (AMPs) are distributed across all kingdoms of life and are an
indispensable component of host defenses. They consist of predominantly short cationic …
indispensable component of host defenses. They consist of predominantly short cationic …
Lessons learned from clinical trials using antimicrobial peptides (AMPs)
GS Dijksteel, MMW Ulrich, E Middelkoop… - Frontiers in …, 2021 - frontiersin.org
Antimicrobial peptides (AMPs) or host defense peptides protect the host against various
pathogens such as yeast, fungi, viruses and bacteria. AMPs also display immunomodulatory …
pathogens such as yeast, fungi, viruses and bacteria. AMPs also display immunomodulatory …
Natural anti-biofilm agents: strategies to control biofilm-forming pathogens
R Mishra, AK Panda, S De Mandal, M Shakeel… - Frontiers in …, 2020 - frontiersin.org
Pathogenic microorganisms and their chronic pathogenicity are significant concerns in
biomedical research. Biofilm-linked persistent infections are not easy to treat due to resident …
biomedical research. Biofilm-linked persistent infections are not easy to treat due to resident …
Antimicrobial peptides as therapeutic agents: Opportunities and challenges
M Mahlapuu, C Björn, J Ekblom - Critical reviews in biotechnology, 2020 - Taylor & Francis
The rapid development of microbial resistance to conventional antibiotics has accelerated
efforts to find anti-infectives with a novel mode-of-action, which are less prone to bacterial …
efforts to find anti-infectives with a novel mode-of-action, which are less prone to bacterial …
Pseudomonas aeruginosa: Infections, Animal Modeling, and Therapeutics
SJ Wood, TM Kuzel, SH Shafikhani - Cells, 2023 - mdpi.com
Pseudomonas aeruginosa is an important Gram-negative opportunistic pathogen which
causes many severe acute and chronic infections with high morbidity, and mortality rates as …
causes many severe acute and chronic infections with high morbidity, and mortality rates as …
Correlation between hemolytic activity, cytotoxicity and systemic in vivo toxicity of synthetic antimicrobial peptides
I Greco, N Molchanova, E Holmedal, H Jenssen… - Scientific reports, 2020 - nature.com
The use of non-standard toxicity models is a hurdle in the early development of antimicrobial
peptides towards clinical applications. Herein we report an extensive in vitro and in vivo …
peptides towards clinical applications. Herein we report an extensive in vitro and in vivo …