Small molecule receptor tyrosine kinase inhibitors (SM-TKIs) are among a group of targeted
cancer therapies, intended to be more specific to cancer cells compared with treatments …

The epidermal growth factor receptor (EGFR) plays a critical role in the tumorigenesis of
various forms of cancer. Targeting the mutant forms of EGFR has been identified as an …

Enhancer of zeste homolog 2 (EZH2) and SET domain bifurcated 1 (SETDB1, also known as
ESET) are oncogenic methyltransferases implicated in a number of human cancers. These …

Arsenic is a well known environmental hazardous material, chronic arsenic exposure results
in different types of liver damage. Among them, liver fibrosis has become a research hotspot …

Zinc finger CCCH-type containing 15 (ZC3H15), a highly conserved protein involved in
several cellular processes, which was responsible for tumorigenesis and may be a …

Cancer stands as a serious malady, posing substantial risks to human well‐being and
survival. This underscores the paramount necessity to explore and investigate novel …

Background: The necroptosis and long noncoding RNA (lncRNA) are critical in the
occurrence and development of malignancy, while the association between the necroptosis …

EGFR mutations have been identified in 20,000 reported NSCLC (non-small cell lung
cancer) samples, and exon 19 deletions and L858R mutations at position 21, known as …

Advanced non-small cell lung cancer (NSCLC) has faced a therapeutic revolution with the
advent of tyrosine kinase inhibitors (TKIs) and immune checkpoints inhibitors (ICIs) …

Epidermal growth factor receptor (EGFR) is a validated drug target for cancer chemotherapy.
Mutations in EGFR are directly linked with the development of drug resistance and this has …