Anaplastic thyroid carcinoma: from clinicopathology to genetics and advanced therapies

E Molinaro, C Romei, A Biagini, E Sabini… - Nature Reviews …, 2017 - nature.com
Anaplastic thyroid carcinoma (ATC) is a rare malignancy, accounting for 1–2% of all thyroid
cancers. Although rare, ATC accounts for the majority of deaths from thyroid carcinoma. ATC …

Molecular genetics and diagnosis of thyroid cancer

YE Nikiforov, MN Nikiforova - Nature Reviews Endocrinology, 2011 - nature.com
Thyroid cancer is a common type of endocrine malignancy, and its incidence has been
steadily increasing in many regions of the world. Initiation and progression of thyroid cancer …

Progress in molecular-based management of differentiated thyroid cancer

M Xing, BR Haugen, M Schlumberger - The Lancet, 2013 - thelancet.com
Substantial developments have occurred in the past 5–10 years in clinical translational
research of thyroid cancer. Diagnostic molecular markers, such as RET-PTC, RAS, and …

Impact of mutational testing on the diagnosis and management of patients with cytologically indeterminate thyroid nodules: a prospective analysis of 1056 FNA …

YE Nikiforov, NP Ohori, SP Hodak… - The Journal of …, 2011 - academic.oup.com
Context: Thyroid nodules are common in adults, but only a small fraction of them is
malignant. Fine-needle aspiration (FNA) cytology provides a definitive diagnosis of benign …

[HTML][HTML] European thyroid association guidelines regarding thyroid nodule molecular fine-needle aspiration cytology diagnostics

R Paschke, S Cantara, A Crescenzi… - European thyroid …, 2017 - etj.bioscientifica.com
Molecular fine-needle aspiration (FNA) cytology diagnostics has the potential to address the
inherent limitation of FNA cytology which is an indeterminate (atypia of undetermined …

Molecular diagnostics of thyroid tumors

YE Nikiforov - Archives of pathology & laboratory medicine, 2011 - meridian.allenpress.com
Context.—Thyroid cancer is the most common type of endocrine malignancy and its
incidence is steadily increasing. Papillary carcinoma and follicular carcinoma are the most …

The treatment of differentiated thyroid cancer in children: emphasis on surgical approach and radioactive iodine therapy

SA Rivkees, EL Mazzaferri, FA Verburg… - Endocrine …, 2011 - academic.oup.com
Pediatric thyroid cancer is a rare disease with an excellent prognosis. Compared with adults,
epithelial-derived differentiated thyroid cancer (DTC), which includes papillary and follicular …

[HTML][HTML] Next-generation sequencing-based multi-gene mutation profiling of solid tumors using fine needle aspiration samples: promises and challenges for routine …

R Kanagal-Shamanna, BP Portier, RR Singh… - Modern pathology, 2014 - Elsevier
Increasing use of fine needle aspiration for oncological diagnosis, while minimally invasive,
poses a challenge for molecular testing by traditional sequencing platforms due to high …

[HTML][HTML] RET/PTC Translocations and Clinico-Pathological Features in Human Papillary Thyroid Carcinoma

C Romei, R Elisei - Frontiers in endocrinology, 2012 - frontiersin.org
Thyroid carcinoma is the most frequent endocrine cancer accounting for 5–10% of thyroid
nodules. Papillary histotype (PTC) is the most prevalent form accounting for 80% of all …

Thyroid nodule guidelines: agreement, disagreement and need for future research

R Paschke, L Hegedüs, E Alexander… - Nature Reviews …, 2011 - nature.com
This article reviews agreement, disagreement and need for future research of the thyroid
nodule guidelines published by the British Thyroid Association, National Cancer Institute …