[HTML][HTML] Natural killer cell-mediated immunotherapy for leukemia

M Allison, J Mathews, T Gilliland, SO Mathew - Cancers, 2022 - mdpi.com
Simple Summary Conventional therapies such as chemotherapy and radiation in leukemia
increase infection susceptibility, adverse side effects and immune cell inactivation. Natural …

Nanomedicine approaches in acute lymphoblastic leukemia

AS Tatar, T Nagy-Simon, C Tomuleasa, S Boca… - Journal of Controlled …, 2016 - Elsevier
Acute lymphoblastic leukemia (ALL) is the malignancy with the highest incidence amongst
children (26% of all cancer cases), being surpassed only by the cancers of the brain and of …

Epigenetic balance ensures mechanistic control of MLL amplification and rearrangement

ZH Gray, D Chakraborty, RR Duttweiler, GD Alekbaeva… - Cell, 2023 - cell.com
Summary MLL/KMT2A amplifications and translocations are prevalent in infant, adult, and
therapy-induced leukemia. However, the molecular contributor (s) to these alterations are …

[PDF][PDF] Islam and Islamic institutions in British Malaya: policies and implementation

M Yegar - 1979 - scholar.archive.org
Hematopoesis is a multi-stage process, which results in development of blood and immande
system's cells. Ikaros, which is coded by IKZF1 and Ikaros faimily zinc finger transcription …

[HTML][HTML] circRNA circAF4 functions as an oncogene to regulate MLL-AF4 fusion protein expression and inhibit MLL leukemia progression

W Huang, K Fang, TQ Chen, ZC Zeng, YM Sun… - Journal of hematology & …, 2019 - Springer
Abstract Background Circular RNAs (circRNAs) represent a type of endogenous noncoding
RNAs that are generated by back-splicing events and favor repetitive sequences. Recent …

[HTML][HTML] Single-cell analysis of childhood leukemia reveals a link between developmental states and ribosomal protein expression as a source of intra-individual …

M Caron, P St-Onge, T Sontag, YC Wang, C Richer… - Scientific reports, 2020 - nature.com
Childhood acute lymphoblastic leukemia (cALL) is the most common pediatric cancer. It is
characterized by bone marrow lymphoid precursors that acquire genetic alterations …

Raman and quantitative phase imaging allow morpho-molecular recognition of malignancy and stages of B-cell acute lymphoblastic leukemia

SK Paidi, P Raj, R Bordett, C Zhang… - Biosensors and …, 2021 - Elsevier
Acute lymphoblastic leukemia (ALL) is one of the most common malignancies that account
for nearly one-third of all pediatric cancers. The current diagnostic assays are time …

Identification and staging of B-cell acute lymphoblastic leukemia using quantitative phase imaging and machine learning

V Ayyappan, A Chang, C Zhang, SK Paidi… - ACS …, 2020 - ACS Publications
Identification and classification of leukemia cells in a rapid and label-free fashion is clinically
challenging and thus presents a prime arena for implementing new diagnostic tools …

[HTML][HTML] Activity of the novel mTOR inhibitor Torin-2 in B-precursor acute lymphoblastic leukemia and its therapeutic potential to prevent Akt reactivation

C Simioni, A Cani, AM Martelli, G Zauli, G Tabellini… - Oncotarget, 2014 - ncbi.nlm.nih.gov
Activity of the novel mTOR inhibitor Torin-2 in B-precursor acute lymphoblastic leukemia and
its therapeutic potential to prevent Akt reactivation - PMC Back to Top Skip to main content NIH …

Ikaros and leukaemia

L Olsson, B Johansson - British journal of haematology, 2015 - Wiley Online Library
The IKZF 1 gene at 7p12. 2 codes for IKAROS (also termed IKZF 1), an essential
transcription factor in haematopoiesis involved primarily in lymphoid differentiation. Its …