Skeletal muscle is the protein reservoir of our body and an important regulator of glucose
and lipid homeostasis. Consequently, the growth or the loss of muscle mass can influence …

Atrophy occurs in specific muscles with inactivity (for example, during plaster cast
immobilization) or denervation (for example, in patients with spinal cord injuries). Muscle …

Stresses like low nutrients, systemic inflammation, cancer or infections provoke a catabolic
state characterized by enhanced muscle proteolysis and amino acid release to sustain liver …

Skeletal muscle mass increases during postnatal development through a process of
hypertrophy, ie enlargement of individual muscle fibers, and a similar process may be …

Skeletal muscle is a plastic organ that is maintained by multiple pathways regulating cell
and protein turnover. During muscle atrophy, proteolytic systems are activated, and …

It has traditionally been believed that resistance training can only induce muscle growth
when the exercise intensity is greater than 65% of the 1-repetition maximum (RM). However …

The loss of skeletal muscle mass under a wide range of acute and chronic maladies is
associated with poor prognosis, reduced quality of life, and increased mortality. Decades of …

Skeletal muscle adapts its mass as consequence of physical activity, metabolism and
hormones. Catabolic conditions or inactivity induce signaling pathways that regulate the …

Skeletal muscle is the dominant organ system in locomotion and energy metabolism.
Postnatal muscle grows and adapts largely by remodelling pre-existing fibres, whereas …

An important unresolved question in skeletal muscle plasticity is whether satellite cells are
necessary for muscle fiber hypertrophy. To address this issue, a novel mouse strain (Pax7 …