Diet and risk of inflammatory bowel disease
V Andersen, A Olsen, F Carbonnel, A Tjønneland… - Digestive and liver …, 2012 - Elsevier
BACKGROUND: A better understanding of the environmental factors leading to inflammatory
bowel disease should help to prevent occurrence of the disease and its relapses. AIM: To …
bowel disease should help to prevent occurrence of the disease and its relapses. AIM: To …
Cannabis pharmacogenomics: a path to personalized medicine
M Babayeva, ZG Loewy - Current Issues in Molecular Biology, 2023 - mdpi.com
Cannabis and related compounds have created significant research interest as a promising
therapy in many disorders. However, the individual therapeutic effects of cannabinoids and …
therapy in many disorders. However, the individual therapeutic effects of cannabinoids and …
Very important pharmacogene summary
LM Hodges, SM Markova, LW Chinn… - Pharmacogenetics …, 2011 - journals.lww.com
ABCB1 (MDR1) is one of many ubiquitous adenosine triphosphate (ATP)-binding cassette
(ABC) genes present in all kingdoms of life that is responsible for cellular homeostasis [1–3] …
(ABC) genes present in all kingdoms of life that is responsible for cellular homeostasis [1–3] …
Polymorphisms in the inflammatory pathway genes TLR2, TLR4, TLR9, LY96, NFKBIA, NFKB1, TNFA, TNFRSF1A, IL6R, IL10, IL23R, PTPN22, and PPARG are …
S Bank, P Skytt Andersen, J Burisch, N Pedersen… - PLoS …, 2014 - journals.plos.org
Background The inflammatory bowel diseases (IBD), Crohn's disease (CD) and ulcerative
colitis (UC), result from the combined effects of susceptibility genes and environmental …
colitis (UC), result from the combined effects of susceptibility genes and environmental …
[HTML][HTML] Polymorphisms in NF-κB, PXR, LXR, PPARγ and risk of inflammatory bowel disease
V Andersen, J Christensen, A Ernst… - World journal of …, 2011 - ncbi.nlm.nih.gov
AIM: To investigate the contribution of polymorphisms in nuclear receptors to risk of
inflammatory bowel disease (IBD). METHODS: Genotypes of nuclear factor (NF)-κB (NFKB1) …
inflammatory bowel disease (IBD). METHODS: Genotypes of nuclear factor (NF)-κB (NFKB1) …
Genetically determined high activities of the TNF-alpha, IL23/IL17, and NFkB pathways were associated with increased risk of ankylosing spondylitis
J Sode, S Bank, U Vogel, PS Andersen… - BMC Medical …, 2018 - Springer
Background Ankylosing spondylitis (AS) results from the combined effects of susceptibility
genes and environmental factors. Polymorphisms in genes regulating inflammation may …
genes and environmental factors. Polymorphisms in genes regulating inflammation may …
Dysregulation of mucosal membrane transporters and drug-metabolizing enzymes in ulcerative colitis
P Erdmann, H Bruckmueller, P Martin, D Busch… - Journal of …, 2019 - Elsevier
Intestinal transporters and metabolizing enzymes are the important factors of the intestinal
absorption barrier. Because there is evidence that their expression and function may be …
absorption barrier. Because there is evidence that their expression and function may be …
Polymorphisms in the xenobiotic transporter Multidrug Resistance 1 (MDR1) and interaction with meat intake in relation to risk of colorectal cancer in a Danish …
V Andersen, M Østergaard, J Christensen, K Overvad… - BMC cancer, 2009 - Springer
Abstract Background The xenobiotic transporters, Multidrug Resistance 1 (MDR1/ABCB1)
and Breast Cancer Resistance Protein (BCRP/ABCG2) may restrict intestinal absorption of …
and Breast Cancer Resistance Protein (BCRP/ABCG2) may restrict intestinal absorption of …
[HTML][HTML] Parthenolide inhibits cancer stem-like side population of nasopharyngeal carcinoma cells via suppression of the NF-κB/COX-2 pathway
K Liao, B Xia, QY Zhuang, MJ Hou, YJ Zhang, B Luo… - Theranostics, 2015 - ncbi.nlm.nih.gov
Cancer stem cells play a central role in the pathogenesis of nasopharyngeal carcinoma and
contribute to both disease initiation and relapse. In this study, cyclooxygenase-2 (COX-2) …
contribute to both disease initiation and relapse. In this study, cyclooxygenase-2 (COX-2) …
ABCB1 and ABCC3 gene polymorphisms are associated with first-year response to methotrexate in juvenile idiopathic arthritis
MCFJ de ROTTE, M Bulatovic, MW Heijstek… - The Journal of …, 2012 - jrheum.org
Objective. Although methotrexate (MTX) is the most widely prescribed drug in juvenile
idiopathic arthritis (JIA), 30% of patients fail to respond to it. To individualize treatment …
idiopathic arthritis (JIA), 30% of patients fail to respond to it. To individualize treatment …