Therapeutic potential of resveratrol: the in vivo evidence

JA Baur, DA Sinclair - Nature reviews Drug discovery, 2006 - nature.com
Resveratrol, a constituent of red wine, has long been suspected to have cardioprotective
effects. Interest in this compound has been renewed in recent years, first from its …

Therapeutic application of anti-arthritis, pain-releasing, and anti-cancer effects of bee venom and its constituent compounds

DJ Son, JW Lee, YH Lee, HS Song, CK Lee… - Pharmacology & …, 2007 - Elsevier
Bee venom (BV) therapy (BVT), the therapeutic application of BV, has been used in
traditional medicine to treat diseases, such as arthritis, rheumatism, pain, cancerous tumors …

Opening of ATP-sensitive potassium channels causes migraine attacks: a new target for the treatment of migraine

MAM Al-Karagholi, JM Hansen, S Guo, J Olesen… - Brain, 2019 - academic.oup.com
Migraine is one of the most disabling and prevalent of all disorders. To improve
understanding of migraine mechanisms and to suggest a new therapeutic target, we …

[PDF][PDF] Chemoprevention by resveratrol: molecular mechanisms and therapeutic potential

S Shankar, G Singh, RK Srivastava - Front Biosci, 2007 - article.imrpress.com
Introduction 3. Mechanisms of Action 3.1. Regulation of Bcl-2 family members 3.2.
Regulation of cell cycle 3.3. Regulation of MAP kinase 3.4. Generation of Reactive Oxygen …

Food pyramid for subjects with chronic pain: foods and dietary constituents as anti-inflammatory and antioxidant agents

M Rondanelli, MA Faliva, A Miccono, M Naso… - Nutrition research …, 2018 - cambridge.org
Emerging literature suggests that diet constituents may play a modulatory role in chronic
pain (CP) through management of inflammation/oxidative stress, resulting in attenuation of …

Potassium channels and pain: present realities and future opportunities

M Ocaña, CM Cendán, EJ Cobos, JM Entrena… - European journal of …, 2004 - Elsevier
Four families of potassium channels with different structures, functional characteristics and
pharmacological sensitivity, are distinguished in neurons: voltage-gated (Kv), calcium …

Resveratrol: preventing properties against vascular alterations and ageing

D Delmas, B Jannin, N Latruffe - Molecular nutrition & food …, 2005 - Wiley Online Library
Cardiovascular diseases are the leading cause of death in developed countries where the
common pathological substrate underlying this process is atherosclerosis. Several new …

The stemness of human ovarian granulosa cells and the role of resveratrol in the differentiation of MSCs—a review based on cellular and molecular knowledge

M Jozkowiak, G Hutchings, M Jankowski, K Kulcenty… - Cells, 2020 - mdpi.com
Ovarian Granulosa Cells (GCs) are known to proliferate in the developing follicle and
undergo several biochemical processes during folliculogenesis. They represent a …

Nitric oxide activates ATP-sensitive potassium channels in mammalian sensory neurons: action by direct S-nitrosylation

T Kawano, V Zoga, M Kimura, MY Liang… - Molecular …, 2009 - journals.sagepub.com
Background ATP-sensitive potassium (KATP) channels in neurons regulate excitability,
neurotransmitter release and mediate protection from cell-death. Furthermore, activation of …

Large-conductance Ca2+-activated K+ channels: physiological role and pharmacology

SN Wu - Current medicinal chemistry, 2003 - ingentaconnect.com
Large-conductance Ca2+-activated K+ (BK-Ca) channels differ from most of other K+
channels in that their activation is under dual control, ie, activated by either increase in …