Effects of astrocytes and microglia on neuroinflammation after spinal cord injury and related immunomodulatory strategies
QM Pang, SY Chen, QJ Xu, M Zhang, DF Liang… - International …, 2022 - Elsevier
Spinal cord injury (SCI) is a catastrophic event which is still without adequate therapies.
Neuroinflammation is the main pathogenesis of secondary damage post-SCI, leading to …
Neuroinflammation is the main pathogenesis of secondary damage post-SCI, leading to …
Spinal cord stimulation paradigms and pain relief: a preclinical systematic review on modulation of the central inflammatory response in neuropathic pain
TJ de Geus, G Franken, EAJ Joosten - Neuromodulation: Technology at the …, 2023 - Elsevier
Objectives Spinal cord stimulation (SCS) is a last-resort treatment for patients with chronic
neuropathic pain. The mechanism underlying SCS and pain relief is not yet fully understood …
neuropathic pain. The mechanism underlying SCS and pain relief is not yet fully understood …
[HTML][HTML] PD-L1 improves motor function and alleviates neuropathic pain in male mice after spinal cord injury by inhibiting MAPK pathway
F Kong, K Sun, J Zhu, F Li, F Lin, X Sun, X Luo… - Frontiers in …, 2021 - frontiersin.org
Background Traumatic spinal cord injury (SCI) causes severe motor dysfunction and
persistent central neuropathic pain (Nep), which has not yet been effectively cured …
persistent central neuropathic pain (Nep), which has not yet been effectively cured …
[HTML][HTML] A therapeutic matrix: virtual reality as a clinical tool for spinal cord injury-induced neuropathic pain
Neuropathic pain (NP) is a chronic, debilitating, and resistant form of pain. The onset rate of
NP following spinal cord injuries (SCI) is high and may reduce the quality of life more than …
NP following spinal cord injuries (SCI) is high and may reduce the quality of life more than …
[HTML][HTML] Comparison of the Effects of Chemokine Receptors CXCR2 and CXCR3 Pharmacological Modulation in Neuropathic Pain Model—In Vivo and In Vitro Study
A Piotrowska, K Ciapała, K Pawlik… - International Journal of …, 2021 - mdpi.com
Recent findings have highlighted the roles of CXC chemokine family in the mechanisms of
neuropathic pain. Our studies provide evidence that single/repeated intrathecal …
neuropathic pain. Our studies provide evidence that single/repeated intrathecal …
Bibliometric study of pain after spinal cord injury
YZ Wang, CC Wu, XQ Wang - Neural Plasticity, 2021 - Wiley Online Library
Background. The prevalence of comorbid pain after spinal cord injury (SCI) is relatively high
in clinical observations and has continued to increase over time. Neuropathic pain (70.14%) …
in clinical observations and has continued to increase over time. Neuropathic pain (70.14%) …
[HTML][HTML] Concise review: Current understanding of extracellular vesicles to treat neuropathic pain
K Zhang, P Li, Y Jia, M Liu, J Jiang - Frontiers in Aging Neuroscience, 2023 - frontiersin.org
Extracellular vesicles (EVs) including exosomes are vesicular vesicles with phospholipid
bilayer implicated in many cellular interactions and have the ability to transfer multiple types …
bilayer implicated in many cellular interactions and have the ability to transfer multiple types …
[HTML][HTML] Future treatment of neuropathic pain in spinal cord injury: the challenges of nanomedicine, supplements or opportunities?
Neuropathic pain (NP) is a common chronic condition that severely affects patients with
spinal cord injuries (SCI). It impairs the overall quality of life and is considered difficult to …
spinal cord injuries (SCI). It impairs the overall quality of life and is considered difficult to …
[HTML][HTML] Feasibility of using remotely delivered Spring Forest Qigong to reduce neuropathic pain in adults with spinal cord injury: a pilot study
A Van de Winckel, ST Carpentier, W Deng… - Frontiers in …, 2023 - frontiersin.org
Introduction: Approximately 69% of 299,000 Americans with spinal cord injury (SCI) suffer
debilitating chronic neuropathic pain, which is intractable to treatment. The aim of this study …
debilitating chronic neuropathic pain, which is intractable to treatment. The aim of this study …
Biodegradable nanoparticles targeting circulating immune cells reduce central and peripheral sensitization to alleviate neuropathic pain following spinal cord injury
MN Saunders, KV Griffin, I Kalashnikova, D Kolpek… - Pain, 2024 - journals.lww.com
Neuropathic pain is a critical source of comorbidity following spinal cord injury (SCI) that can
be exacerbated by immune-mediated pathologies in the central and peripheral nervous …
be exacerbated by immune-mediated pathologies in the central and peripheral nervous …