Advances in microfluidics for single red blood cell analysis

GV Grigorev, AV Lebedev, X Wang, X Qian… - Biosensors, 2023 - mdpi.com
The utilizations of microfluidic chips for single RBC (red blood cell) studies have attracted
great interests in recent years to filter, trap, analyze, and release single erythrocytes for …

Engineering Synthetic Erythrocytes as Next‐Generation Blood Substitutes

FL Gomes, SH Jeong, SR Shin, J Leijten… - Advanced Functional …, 2024 - Wiley Online Library
Blood scarcity is one of the main causes of healthcare disruptions worldwide, with blood
shortages occurring at an alarming rate. Over the last decades, blood substitutes have …

A computational study of red blood cell deformability effect on hemodynamic alteration in capillary vessel networks

S Ebrahimi, P Bagchi - Scientific reports, 2022 - nature.com
Capillary blood vessels, the smallest vessels in the body, form an intricate network with
constantly bifurcating, merging and winding vessels. Red blood cells (RBCs) must navigate …

[HTML][HTML] Red blood cells tracking and cell-free layer formation in a microchannel with hyperbolic contraction: A CFD model validation

M Gracka, R Lima, JM Miranda, S Student… - Computer Methods and …, 2022 - Elsevier
Abstract Background and Objective In recent years, progress in microfabrication
technologies has attracted the attention of researchers across disciplines. Microfluidic …

The influence of red blood cell deformability on hematocrit profiles and platelet margination

B Czaja, M Gutierrez, G Závodszky… - PLOS Computational …, 2020 - journals.plos.org
The influence of red blood cell (RBC) deformability in whole blood on platelet margination is
investigated using confocal microscopy measurements of flowing human blood and cell …

Temporal-spatial heterogeneity of hematocrit in microvascular networks

G Li, T Ye, B Yang, S Wang, X Li - Physics of Fluids, 2023 - pubs.aip.org
Hematocrit, defined as the volume percentage of red blood cells in blood, is an important
indicator of human health status, which demonstrates the capability of blood to deliver …

Numerical simulation of blood flow modeled as a fluid-particulate mixture

K Chandran, IS Dalal, K Tatsumi… - Journal of Non-Newtonian …, 2020 - Elsevier
ABSTRACT A continuum model for the transport of red blood cells (RBC) inside arteries and
capillaries of small diameters is proposed. The pressure and velocity fields are solved using …

The impact of hemodynamic factors in a coronary main artery to detect the atherosclerotic severity: Single and multiple sequential stenosis cases

KE Hoque, M Ferdows, S Sawall, EE Tzirtzilakis… - Physics of …, 2021 - pubs.aip.org
A conventional invasive catheterization procedure is currently used to detect atherosclerotic
severity in coronary arteries. However, it is still challenging to measure multiple consecutive …

Cell-free layer of red blood cells in a constricted microfluidic channel under steady and time-dependent flow conditions

SM Recktenwald, K Graessel, Y Rashidi, JN Steuer… - Physical Review …, 2023 - APS
Constricted blood vessels in the circulatory system can severely impact the spatiotemporal
organization of red blood cells (RBCs) causing various physiological complications. In …

[图书][B] Vascular Biomechanics

TC Gasser - 2021 - Springer
The development of the vascular system was a critical step in the evolution of species. It
allowed organisms to meet the growing metabolic demands and opened the door for the …