Cancer stem cells (CSCs) have been identified as rare cell populations in many cancers,
including leukemia and solid tumors. Accumulating evidence has suggested that CSCs are …

Cancer Stem Cells | New England Journal of Medicine Skip to main content The New England
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In this study we interrogated the metabolome of human acute myeloid leukemia (AML) stem
cells to elucidate properties relevant to therapeutic intervention. We demonstrate that amino …

Recent studies have described malignant stem cells as central to the initiation, growth, and
potential relapse of acute and chronic myelogenous leukemia (AML and CML). Because of …

Leukemia stem cells (LSCs) are thought to play a central role in the pathogenesis of acute
leukemia and likely contribute to both disease initiation and relapse. Therefore, identification …

Major strides have been made in our understanding of the molecular basis of adult and
pediatric leukemias. More than one hundred disease alleles have been identified and …

Since last two decades, the major cancer research has focused on understanding the
characteristic properties and mechanism of formation of Cancer stem cells (CSCs), due to …

Accumulating evidence indicates that breast cancer is caused by cancer stem cells and cure
of breast cancer requires eradication of breast cancer stem cells. Previous studies with …

Cancer stem cells can generate tumors from only a small number of cells, whereas
differentiated cancer cells cannot. The prominent feature of cancer stem cells is its ability to …

Acute myeloid leukemia (AML) is a life-threatening stem cell disease characterized by
uncontrolled proliferation and accumulation of myeloblasts. Using an advanced RNAi …