New insights into the therapeutic potentials of statins in cancer

C Liu, H Chen, B Hu, J Shi, Y Chen… - Frontiers in …, 2023 - frontiersin.org
The widespread clinical use of statins has contributed to significant reductions of
cardiovascular morbidity and mortality. Increasing preclinical and epidemiological …

[HTML][HTML] Acetyl-CoA metabolism as a therapeutic target for cancer

G Chen, B Bao, Y Cheng, M Tian, J Song… - Biomedicine & …, 2023 - Elsevier
Acetyl-coenzyme A (acetyl-CoA), an essential metabolite, not only takes part in numerous
intracellular metabolic processes, powers the tricarboxylic acid cycle, serves as a key hub …

Exploring the role of the inflammasomes on prostate cancer: Interplay with obesity

JM Pérez-Gómez, AJ Montero-Hidalgo… - Reviews in Endocrine …, 2023 - Springer
Obesity is a weight-related disorder characterized by excessive adipose tissue growth and
dysfunction which leads to the onset of a systemic chronic low-grade inflammatory state …

Fatty acid binding protein 5 regulates docetaxel sensitivity in taxane-resistant prostate cancer cells

A Hillowe, C Gordon, L Wang, RC Rizzo, LC Trotman… - Plos one, 2023 - journals.plos.org
Prostate cancer is a leading cause of cancer-related deaths in men in the United States.
Although treatable when detected early, prostate cancer commonly transitions to an …

Antidiabetic potential of Carica papaya L. and its constituents: From folkloric uses to products development

AD Ogunlakin, TR Onifade, OA Ojo… - Bioactive Compounds in …, 2023 - ffhdj.com
Carica papaya L. is a plant that has a reputation for being antidiabetic. This review is
focused on antidiabetic properties of Carica papaya. A comprehensive search was …

New insights into lipid metabolism and prostate cancer

Z Zhang, W Wang, P Kong, K Feng… - International …, 2023 - spandidos-publications.com
Prostate cancer (PCa) is the most common malignant tumor of the male urological system
and poses a severe threat to the survival of middle‑aged and elderly males worldwide. The …

[HTML][HTML] Periprostatic Adipose Tissue: A New Perspective for Diagnosing and Treating Prostate Cancer

H Cao, Y Wang, D Zhang, B Liu, H Zhou… - Journal of …, 2024 - ncbi.nlm.nih.gov
Prostate cancer (PCa) is the most common tumor of the male genitourinary system. It will
eventually progress to fatal metastatic castration-resistant prostate cancer, for which …

Fatty acid diet and prostate cancer: a treasure hunt or a wild goose chase?

G Mjaess, T Roumeguère, K Korpak… - Prostate Cancer and …, 2024 - nature.com
While there are several factors that contribute to cancer development, mounting evidence
suggests that dietary lipids may play an important role. The idea that what we eat could …

Unlocking ferroptosis in prostate cancer—the road to novel therapies and imaging markers

PHA Cao, A Dominic, FE Lujan, S Senthilkumar… - Nature Reviews …, 2024 - nature.com
Ferroptosis is a distinct form of regulated cell death that is predominantly driven by the build-
up of intracellular iron and lipid peroxides. Ferroptosis suppression is widely accepted to …

Adiponcosis interplay: adipose tissue, microenvironment and prostate cancer

E Di Zazzo, B Barone, F Crocetto - Journal of Basic and Clinical …, 2024 - degruyter.com
The word “Adiponcosis,” surfaced in 2013 from the fusion of the two words “adiposis” and
“oncosis”, was introduced to highlight the complex and multifactorial relationship between …