Revisiting fibrosis in inflammatory bowel disease: the gut thickens

S D'Alessio, F Ungaro, D Noviello, S Lovisa… - Nature Reviews …, 2022 - nature.com
Intestinal fibrosis, which is usually the consequence of chronic inflammation, is a common
complication of inflammatory bowel disease (IBD), including Crohn's disease and ulcerative …

ECCO-ESGAR topical review on optimizing reporting for cross-sectional imaging in inflammatory bowel disease

T Kucharzik, J Tielbeek, D Carter… - Journal of Crohn's …, 2022 - academic.oup.com
Abstract Background and Aims The diagnosis and follow up of patients with inflammatory
bowel disease [IBD] requires cross-sectional imaging modalities, such as intestinal …

Mechanism of fibrosis and stricture formation in Crohn's disease

J Alfredsson, MJ Wick - Scandinavian Journal of Immunology, 2020 - Wiley Online Library
Crohn's disease (CD) is a chronic inflammatory disease of the gastrointestinal tract that
leads to substantial suffering for millions of patients. In some patients, the chronic …

[HTML][HTML] Ultrasound elastography

XW Cui, KN Li, AJ Yi, B Wang, Q Wei, GG Wu… - Endoscopic …, 2022 - journals.lww.com
Physicians have used palpation as a diagnostic examination to understand the elastic
properties of pathology for a long time since they realized that tissue stiffness is closely …

Crohn's disease related strictures in cross‐sectional imaging: More than meets the eye?

J Sleiman, P Chirra, NS Gandhi… - United European …, 2022 - Wiley Online Library
Strictures in Crohn's disease (CD) are a hallmark of long‐standing intestinal damage,
brought about by inflammatory and non‐inflammatory pathways. Understanding the complex …

[HTML][HTML] Fibro-stenosing Crohn's disease: what is new and what is next?

V Solitano, A Dal Buono, R Gabbiadini… - Journal of Clinical …, 2023 - mdpi.com
Fibro-stenosing Crohn's disease (CD) is a common disease presentation that leads to
impaired quality of life and often requires endoscopic treatments or surgery. From a …

Recent advances in intestinal fibrosis

MV Lenti, G Santacroce, G Broglio, CM Rossi… - Molecular Aspects of …, 2024 - Elsevier
Despite many progresses have been made in the treatment of inflammatory bowel disease,
especially due to the increasing number of effective therapies, the development of tissue …

Prevention and treatment of stricturing Crohn's Disease–perspectives and challenges

J Sleiman, S El Ouali, T Qazi, B Cohen… - Expert review of …, 2021 - Taylor & Francis
Introduction: Fibrostenosis is a hallmark of Crohn's disease (CD), remains a challenge in
today's clinical management of inflammatory bowel disease patients and represents a key …

[HTML][HTML] The role of genetic and epigenetic regulation in Intestinal Fibrosis in Inflammatory Bowel Disease: a descending process or a programmed consequence?

S Jarmakiewicz-Czaja, A Sokal, K Ferenc, E Motyka… - Genes, 2023 - mdpi.com
Inflammatory bowel diseases (IBDs) are a group of chronic diseases characterized by
recurring periods of exacerbation and remission. Fibrosis of the intestine is one of the most …

[HTML][HTML] Crohn's disease at radiological imaging: focus on techniques and intestinal tract

G Cicero, S Mazziotti - Intest Res, 2021 - synapse.koreamed.org
Over recent years, inflammatory bowel diseases have become an issue of increased
attention in daily clinical practice, due to both a rising incidence and improved imaging …