Basic mechanisms of diabetic heart disease

RH Ritchie, ED Abel - Circulation research, 2020 - Am Heart Assoc
Diabetes mellitus predisposes affected individuals to a significant spectrum of
cardiovascular complications, one of the most debilitating in terms of prognosis is heart …

[HTML][HTML] Diabetes mellitus and heart failure

M Lehrke, N Marx - The American journal of cardiology, 2017 - Elsevier
Epidemiologic and clinical data from the last 2 decades have shown that the prevalence of
heart failure in diabetes is very high, and the prognosis for patients with heart failure is …

Implications of underlying mechanisms for the recognition and management of diabetic cardiomyopathy

TH Marwick, R Ritchie, JE Shaw, D Kaye - Journal of the American College …, 2018 - jacc.org
Heart failure is a complex clinical syndrome, the incidence and prevalence of which is
increased in diabetes mellitus, pre-diabetes, and obesity. Although this may arise from …

The diabetic cardiomyopathy: the contributing pathophysiological mechanisms

T Salvatore, PC Pafundi, R Galiero, G Albanese… - Frontiers in …, 2021 - frontiersin.org
Individuals with diabetes mellitus (DM) disclose a higher incidence and a poorer prognosis
of heart failure (HF) than non-diabetic people, even in the absence of other HF risk factors …

Association between prediabetes and adverse outcomes in heart failure

L Mai, W Wen, M Qiu, X Liu, L Sun… - Diabetes, Obesity …, 2021 - Wiley Online Library
Aims Patients with heart failure (HF) and with diabetes experienced significantly worse
outcomes than those without diabetes. However, data on the prognostic impact of …

Diabetes and pre‐diabetes in patients with heart failure and preserved ejection fraction

AM Jackson, R Rørth, J Liu… - European Journal of …, 2022 - Wiley Online Library
Aim There is an association between heart failure with preserved ejection fraction (HFpEF)
and insulin resistance, but less is known about the diabetic continuum, and in particular …

Abnormal myocardial dietary fatty acid metabolism and diabetic cardiomyopathy

AC Carpentier - Canadian Journal of Cardiology, 2018 - Elsevier
Patients with diabetes are at very high risk of hospitalization and death from heart failure.
Increased prevalence of coronary heart disease, hypertension, autonomic neuropathy, and …

Type 2 diabetes and heart failure: characteristics and prognosis in preserved, mid-range and reduced ventricular function

I Johansson, U Dahlström, M Edner… - Diabetes and …, 2018 - journals.sagepub.com
Objective: To study the characteristics and prognostic implications of type 2 diabetes in
different heart failure entities from a nationwide perspective. Methods: This observational …

Loss of Lipocalin 10 Exacerbates Diabetes-Induced Cardiomyopathy via Disruption of Nr4a1-Mediated Anti-Inflammatory Response in Macrophages

Q Li, Y Li, W Huang, X Wang, Z Liu, J Chen… - Frontiers in …, 2022 - frontiersin.org
Metabolic disorders (ie, hyperglycemia, hyperlipidemia, and hyperinsulinemia) cause
increased secretion of inflammatory cytokines/chemokines, leading to gradual loss of …

Atherosclerotic cardiovascular disease and heart failure: determinants of risk and outcomes in patients with diabetes

AJ Nelson, ED Peterson, NJ Pagidipati - Progress in cardiovascular …, 2019 - Elsevier
Cardiovascular disease (CVD) is the most common cause of morbidity and mortality for
patients with diabetes mellitus (DM). Although the burden of atherosclerotic CVD (ASCVD) is …