[HTML][HTML] Lipoprotein (a) beyond the kringle IV repeat polymorphism: the complexity of genetic variation in the LPA gene
S Coassin, F Kronenberg - Atherosclerosis, 2022 - Elsevier
Abstract High lipoprotein (a)[Lp (a)] concentrations are one of the most important genetically
determined risk factors for cardiovascular disease. Lp (a) concentrations are an enigmatic …
determined risk factors for cardiovascular disease. Lp (a) concentrations are an enigmatic …
DNA methylation as a mediator of associations between the environment and chronic diseases: A scoping review on application of mediation analysis
ABSTRACT DNA methylation (DNAm) is one of the most studied epigenetic modifications.
DNAm has emerged as a key biological mechanism and biomarkers to test associations …
DNAm has emerged as a key biological mechanism and biomarkers to test associations …
Lipoprotein (a): when to measure and how to treat?
D Rhainds, MR Brodeur, JC Tardif - Current Atherosclerosis Reports, 2021 - Springer
Abstract Purpose of Review The purpose of this article is to review current evidence for
lipoprotein (a)(Lp (a)) as a risk factor for multiple cardiovascular (CV) disease phenotypes …
lipoprotein (a)(Lp (a)) as a risk factor for multiple cardiovascular (CV) disease phenotypes …
[HTML][HTML] The effect of LPA Thr3888Pro on lipoprotein (a) and coronary artery disease is modified by the LPA KIV-2 variant 4925G> A
R Grüneis, C Lamina, S Di Maio, S Schönherr… - Atherosclerosis, 2022 - Elsevier
Background and aims High lipoprotein (a)[Lp (a)] concentrations are associated with
increased coronary artery disease (CAD) risk. Lp (a) is regulated mainly genetically by the …
increased coronary artery disease (CAD) risk. Lp (a) is regulated mainly genetically by the …
Epigenome‐wide association study of BMI in Black populations from InterGEN and GENOA
Objective Obesity is a significant public health concern across the globe. Research
investigating epigenetic mechanisms related to obesity and obesity‐associated conditions …
investigating epigenetic mechanisms related to obesity and obesity‐associated conditions …
DNA methylation profiling identifies a high effect genetic variant for lipoprotein (a) levels
Changes in whole blood DNA methylation levels at several CpG sites have been associated
with circulating blood lipids, specifically high-density lipoprotein and triglycerides. This study …
with circulating blood lipids, specifically high-density lipoprotein and triglycerides. This study …
Genetics of Lipoprotein (a)
G Utermann - Lipoprotein (a), 2023 - Springer
Abstract Lipoprotein (a)(Lp (a)) is a macromolecular complex consisting of LDL and the
characteristic apolipoprotein (a)(apo (a)). Lp (a) occurs as a quantitative genetic trait with …
characteristic apolipoprotein (a)(apo (a)). Lp (a) occurs as a quantitative genetic trait with …
60 Years of Lp (a) Research: From Ouchterlonys Double Diffusion to Copy Number Variation and a Significant Risk Factor for CHD
G Utermann - Lipoprotein (a), 2023 - Springer
In this article, key events of the history of lipoprotein (a)(Lp (a)) research from its discovery as
a genetic trait in human plasma by the Norwegian scientist Kare Berg in 1963 until the …
a genetic trait in human plasma by the Norwegian scientist Kare Berg in 1963 until the …