PACSIN proteins in vivo: Roles in development and physiology

V Dumont, S Lehtonen - Acta Physiologica, 2022 - Wiley Online Library
Protein kinase C and casein kinase substrate in neurons (PACSINs), or syndapins (synaptic
dynamin‐associated proteins), are a family of proteins involved in the regulation of cell …

Non-apoptotic Fas signaling

H Wajant, K Pfizenmaier, P Scheurich - Cytokine & growth factor reviews, 2003 - Elsevier
Fas (Apo-1, CD95) and Fas-Ligand (FasL, CD95L) are typical members of the TNF receptor
and TNF ligand family, respectively, with a pivotal role in the regulation of apoptotic …

Molecular basis for SH3 domain regulation of F-BAR–mediated membrane deformation

Y Rao, Q Ma, A Vahedi-Faridi… - Proceedings of the …, 2010 - National Acad Sciences
Members of the Bin/amphiphysin/Rvs (BAR) domain protein superfamily are involved in
membrane remodeling in various cellular pathways ranging from endocytic vesicle and T …

The syndapin protein family: linking membrane trafficking with the cytoskeleton

MM Kessels, B Qualmann - Journal of cell science, 2004 - journals.biologists.com
Syndapins–also called PACSINs–are highly conserved Src-homology 3 (SH3)-domain-
containing proteins that seem to exist in all multicellular eukaryotes. They interact with the …

Role of metalloproteases in the CD95 signaling pathways

L Devel, N Guedeney, S Bregant… - Frontiers in …, 2022 - frontiersin.org
CD95L (also known as FasL or CD178) is a member of the tumor necrosis family (TNF)
superfamily. Although this transmembrane ligand has been mainly considered as a potent …

Insights into the molecular regulation of FasL (CD178) biology

M Lettau, M Paulsen, H Schmidt, O Janssen - European journal of cell …, 2011 - Elsevier
Fas ligand (FasL, CD95L, APO-1L, CD178, TNFSF6, APT1LG1) is the key death factor of
receptor-triggered programmed cell death in immune cells. FasL/Fas-dependent apoptosis …

Intra-and extracellular effector vesicles from human T and NK cells: same-same, but different?

M Lettau, O Janssen - Frontiers in Immunology, 2021 - frontiersin.org
Cytotoxic T lymphocytes (CTL) and Natural Killer (NK) cells utilize an overlapping effector
arsenal for the elimination of target cells. It was initially proposed that all cytotoxic effector …

CD95 ligand-death factor and costimulatory molecule?

O Janssen, J Qian, A Linkermann… - Cell Death & …, 2003 - nature.com
The CD95 ligand is involved as a death factor in the regulation of activation-induced cell
death, establishment of immune privilege and tumor cell survival. In addition, CD95L may …

Pombe Cdc15 homology (PCH) proteins: coordinators of membrane–cytoskeletal interactions

V Chitu, ER Stanley - Trends in cell biology, 2007 - cell.com
Cellular adhesion, motility, endocytosis, exocytosis and cytokinesis involve the coordinated
reorganization of the cytoskeleton and of the plasma membrane. The 'Pombe Cdc15 …

Life in the Fas lane: differential outcomes of Fas signaling

E Brint, G O'Callaghan, A Houston - Cellular and Molecular Life Sciences, 2013 - Springer
Fas, also known as CD95 or APO-1, is a member of the tumor necrosis factor/nerve growth
factor superfamily. Although best characterized in terms of its apoptotic function, recent …