Abstract Purpose of Review We review non-pharmacological and pharmacological
approaches to managing behavioral and psychological symptoms of dementia (BPSD). We …

Dementia with Lewy bodies and Parkinson's disease dementia, jointly known as Lewy body
dementia, are common neurodegenerative conditions. Patients with Lewy body dementia …

Importance Approximately one-third of patients with major depressive disorder (MDD) do not
respond to available antidepressants. Objective To assess the efficacy, safety, and dose …

Medications to treat disease and extend life in our patients often amass in quantities,
resulting in what has been termed “polypharmacy.” This imprecise label usually describes …

Behavioural and psychological symptoms of dementia (BPSD) occur in most patients with
dementia. They cause great suffering in patients and caregivers, sometimes more so than …

Background Patients with dementia due to neurodegenerative disease can have dementia-
related psychosis. The effects of the oral 5-HT2A inverse agonist and antagonist …

Stigma negatively impact quality of life of people with dementia and their family members.
Yet the literature in stigma and dementia remains scant. This article systematically reviews …

The objective of this study was to assess international trends in antipsychotic use, using a
standardised methodology. A repeated cross-sectional design was applied to data extracts …

Importance Agitation is a prevalent, distressing, and burdensome manifestation of Alzheimer
dementia in need of an efficacious, safe, and well-tolerated treatment. Objective To confirm …

Background: The purpose of this review is to evaluate the data on the use of antipsychotics
in individuals with dementia from meta-analyses. Methods: We performed a literature search …