DNA binding studies of antifungal drug posaconazole using spectroscopic and molecular docking methods
The binding studies of DNA with small molecules have been an emerging field of research
all the time since DNA as the genetic material is a major biological target for various drugs …
all the time since DNA as the genetic material is a major biological target for various drugs …
[HTML][HTML] Intrinsically fluorescent anti-cancer drugs
Simple Summary Cancer is one of the biggest causes of death world-wide. The
development of anti-cancer drugs is important in combatting this disease. As good as these …
development of anti-cancer drugs is important in combatting this disease. As good as these …
The interaction mechanism of candidone with calf thymus DNA: A multi-spectroscopic and MD simulation study
In this investigation, the effects of candidone on the structure and conformation of DNA were
evaluated by spectroscopic methods, molecular dynamics simulation, and molecular …
evaluated by spectroscopic methods, molecular dynamics simulation, and molecular …
Investigation of the interaction between anticancer drug ibrutinib and double-stranded DNA by electrochemical and molecular docking techniques
Ibrutinib is Bruton's tyrosine kinase inhibitor that is generally used in the treatment of
lymphoma. The investigation of anticancer drug-double-stranded DNA (dsDNA) interaction …
lymphoma. The investigation of anticancer drug-double-stranded DNA (dsDNA) interaction …
Toxicity assessment of carmine and its interaction with calf thymus DNA
Carmine (CRM) is a colouring agent, extensively used in a variety of foods, beverages,
cosmetics and pharmaceuticals. A battery of in vitro toxicity tests and chemical interaction …
cosmetics and pharmaceuticals. A battery of in vitro toxicity tests and chemical interaction …
Synthesis, characterization and biological applications of a new nano-sized binuclear copper (II) complex containing bathophenanthroline and ellagic acid as ligands
A new binuclear copper (II) complex, nano-[Cu 2-(DIP) 2-EA], was synthesized by using
bathophenanthroline and ellagic acid ligands in a multi-component/one-pot method, and …
bathophenanthroline and ellagic acid ligands in a multi-component/one-pot method, and …
Synthesis, crystallographic, DNA binding, and molecular docking/dynamic studies of a privileged chalcone-sulfonamide hybrid scaffold as a promising anticancer …
In the present study, a drug-like molecular hybrid structure between chalcone and
sulfonamide moieties was synthesized and characterized. The structural peculiarities of the …
sulfonamide moieties was synthesized and characterized. The structural peculiarities of the …
Multi-spectroscopic characteristics of olive oil-based Quercetin nanoemulsion (QuNE) interactions with calf thymus DNA and its anticancer activity
Several types of biological functions have been reported for Quercetin, such as antioxidant
and anticancer activities. The current study aimed to improve the solubility and stability of …
and anticancer activities. The current study aimed to improve the solubility and stability of …
Investigation of binding characteristics of ritonavir with calf thymus DNA with the help of spectroscopic techniques and molecular simulation
SB Kou, KL Zhou, ZY Lin, YY Lou… - Journal of …, 2022 - Taylor & Francis
The binding behavior of ritonavir (RTV), a HIV/AIDS protease inhibitor, with ct-DNA was
characterized through multiple testing technologies and theoretical calculation. The findings …
characterized through multiple testing technologies and theoretical calculation. The findings …
DNA groove binder and significant cytotoxic activity on human colon cancer cells: Potential of a dimeric zinc (II) phthalocyanine derivative
GS Batibay, GK Karaoglan, GG Kose… - Biophysical …, 2023 - Elsevier
The interaction of a multi-component system consisting of benzene-1, 4-diyldimethanimine-
bridged dimeric zinc-phthalocyanine groups (4OMPCZ) with calf thymus DNA (ct-DNA) was …
bridged dimeric zinc-phthalocyanine groups (4OMPCZ) with calf thymus DNA (ct-DNA) was …