Genetics and biology of pancreatic ductal adenocarcinoma
With 5-year survival rates remaining constant at 6% and rising incidences associated with
an epidemic in obesity and metabolic syndrome, pancreatic ductal adenocarcinoma (PDAC) …
an epidemic in obesity and metabolic syndrome, pancreatic ductal adenocarcinoma (PDAC) …
Mesoporous silica nanoparticle-supported lipid bilayers (protocells) for active targeting and delivery to individual leukemia cells
Many nanocarrier cancer therapeutics currently under development, as well as those used
in the clinical setting, rely upon the enhanced permeability and retention (EPR) effect to …
in the clinical setting, rely upon the enhanced permeability and retention (EPR) effect to …
Polymeric nanoparticles-siRNA as an emerging nano-polyplexes against ovarian cancer
Ovarian cancer (OC) is considered fifth-deadliest cancer globally responsible for high
mortality in women. As the conventional therapeutic and diagnostic approaches are …
mortality in women. As the conventional therapeutic and diagnostic approaches are …
Ligand-targeted theranostic nanomedicines against cancer
Nanomedicines have significant potential for cancer treatment. Although the majority of
nanomedicines currently tested in clinical trials utilize simple, biocompatible liposome …
nanomedicines currently tested in clinical trials utilize simple, biocompatible liposome …
Delivery of small interfering RNA to inhibit vascular endothelial growth factor in zebrafish using natural brain endothelia cell-secreted exosome nanovesicles for the …
Although small interfering RNA (siRNA) holds great therapeutic promise, its delivery to the
disease site remains a paramount obstacle. In this study, we tested whether brain …
disease site remains a paramount obstacle. In this study, we tested whether brain …
Protocells: modular mesoporous silica nanoparticle‐supported lipid bilayers for drug delivery
Mesoporous silica nanoparticle‐supported lipid bilayers, termed 'protocells,'represent a
potentially transformative class of therapeutic and theranostic delivery vehicle. The field of …
potentially transformative class of therapeutic and theranostic delivery vehicle. The field of …
Gold nanoparticle size and shape effects on cellular uptake and intracellular distribution of siRNA nanoconstructs
Gold nanoparticles (AuNPs) show potential for transfecting target cells with small interfering
RNA (siRNA), but the influence of key design parameters such as the size and shape of the …
RNA (siRNA), but the influence of key design parameters such as the size and shape of the …
Current progress and outlook of nano-based hydrogel dressings for wound healing
X Zhang, P Wei, Z Yang, Y Liu, K Yang, Y Cheng… - Pharmaceutics, 2022 - mdpi.com
Wound dressing is an important tool for wound management. Designing wound dressings
by combining various novel materials and drugs to optimize the peri-wound environment …
by combining various novel materials and drugs to optimize the peri-wound environment …
Near infrared-guided smart nanocarriers for microRNA-controlled release of doxorubicin/siRNA with intracellular ATP as fuel
In chemotherapy, it is a great challenge to recruit endogenous stimuli instead of external
intervention for targeted delivery and controlled release; microRNAs are the most promising …
intervention for targeted delivery and controlled release; microRNAs are the most promising …
Emerging roles for lncRNA-NEAT1 in colorectal cancer
S Azizidoost, F Ghaedrahmati, O Anbiyaee… - Cancer cell …, 2022 - Springer
Colorectal cancer (CRC) is the third cause of cancer death in the world that arises from the
glandular and epithelial cells of the large intestine, during a series of genetic or epigenetic …
glandular and epithelial cells of the large intestine, during a series of genetic or epigenetic …