This review is written with the purpose to review the current nanomedicine literature and
provide an outlook on the developments in utilizing nanoscale drug constructs in treatment …

New polymeric biomaterials and nanomedicines targeting cancer cells are highly required
because of their potential clinical applications. Gene therapy enjoys high popularity as …

Background Traumatic spinal cord injury (SCI) includes the primary insult as well as a
sequela of biochemical and cellular cascades that amplifies the initial injury. This …

Background: Gene therapy is a new approach to discover and treat many diseases. It has
attracted considerable attention from researchers in the last decades. The gene therapy …

Periostin is a modular glycoprotein frequently observed to be a major constituent of the
extracellular milieu of mass-forming intrahepatic cholangiocarcinoma and other …

Gene silencing using small interfering RNA (siRNA) relies on the critical need for a safe and
effective carrier, capable of strong but reversible complexation, siRNA protection, cellular …

Abstract Purpose of Review The clinical significance, target pathways, recent successes,
and challenges that preclude translation of RNAi bone regenerative approaches are …

The present study investigated the concurrent delivery of antineoplastic drug, doxorubicin,
and HER2 siRNA through a targeted theranostic metallic gold nanoparticle designed using …

Pulmonary fibrosis (PF) is the end stage of severe lung diseases, in which the lung
parenchyma is replaced by fibrous scar tissue. The result is a remarkable reduction in …

Delivery of small-interfering RNA (siRNA) has been of great interest in the past decade for
effective gene silencing. To overcome synthetic and regulatory challenges posed by …