Micro-fragmented adipose tissue as a natural scaffold for targeted drug delivery in brain cancer
A Salagean, A Nechifor-Boila, N Bajwa… - International Journal of …, 2023 - mdpi.com
Major limitations in the effective treatment of neurological cancer include systemic
cytotoxicity of chemotherapy, inaccessibility, and inoperability. The capability to successfully …
cytotoxicity of chemotherapy, inaccessibility, and inoperability. The capability to successfully …
Application of emerging technologies in ischemic stroke: from clinical study to basic research
Q Chen, S Zhang, W Liu, X Sun, Y Luo… - Frontiers in Neurology, 2024 - frontiersin.org
Stroke is a primary cause of noncommunicable disease-related death and disability
worldwide. The most common form, ischemic stroke, is increasing in incidence resulting in a …
worldwide. The most common form, ischemic stroke, is increasing in incidence resulting in a …
Preconditioning with interleukin-1 alpha is required for the neuroprotective properties of mesenchymal stem cells after ischemic stroke in mice
Mesenchymal stem cell (MSC) pre-conditioning with interleukin-1 alpha (IL-1ɑ) drives MSCs
toward a potent anti-inflammatory phenotype. The aim of this study was to assess the …
toward a potent anti-inflammatory phenotype. The aim of this study was to assess the …
Advances in stem cell therapy: new applications and innovative therapeutic approaches
A Marcuzzi, N Maximova - Frontiers in Medicine, 2023 - frontiersin.org
Stem cell therapy has continued to advance, bringing hope to cure diseases that were once
considered incurable. The concepts underlying the use of stem cells in therapy depend on …
considered incurable. The concepts underlying the use of stem cells in therapy depend on …
Re-establishing immune tolerance in multiple sclerosis: focusing on novel mechanisms of mesenchymal stem cell regulation of Th17/Treg balance
H Hu, H Li, R Li, P Liu, H Liu - Journal of Translational Medicine, 2024 - Springer
Abstract The T-helper 17 (Th17) cell and regulatory T cell (Treg) axis plays a crucial role in
the development of multiple sclerosis (MS), which is regarded as an immune imbalance …
the development of multiple sclerosis (MS), which is regarded as an immune imbalance …
Inflammatory diseases: Function of LncRNAs in their emergence and the role of mesenchymal stem cell secretome in their treatment
One of the best treatments for inflammatory diseases such as COVID− 19, respiratory
diseases and brain diseases is treatment with stem cells. Here we investigate the effect of …
diseases and brain diseases is treatment with stem cells. Here we investigate the effect of …
Tumor Necrosis Factor Alpha Preconditioned Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles Enhance the Inhibition of Necroptosis of Acinar …
W Xie, T Luo, Z Ma, S Xue, X Jia, T Yang… - … Engineering Part A, 2023 - liebertpub.com
Severe acute pancreatitis (SAP) is a common abdominal emergency with a high mortality
rate and a lack of effective therapeutic options. Although mesenchymal stem cell (MSC) …
rate and a lack of effective therapeutic options. Although mesenchymal stem cell (MSC) …
Mesenchymal stem cell-based therapies for treating well-studied neurological disorders: a systematic review
GD Patel, L Liu, A Li, YH Yang, CC Shen… - Frontiers in …, 2024 - frontiersin.org
Background Millions of people across the globe are affected by conditions like Amyotrophic
Lateral Sclerosis (ALS), Parkinson's Disease (PD), Multiple Sclerosis (MS), Spinal Cord …
Lateral Sclerosis (ALS), Parkinson's Disease (PD), Multiple Sclerosis (MS), Spinal Cord …
Role of intracranial bone marrow mesenchymal stem cells in stroke recovery: A focus on post-stroke inflammation and mitochondrial transfer
J Ming, Y Liao, W Song, Z Wang, J Cui, L He, G Chen… - Brain Research, 2024 - Elsevier
Stem cell therapy has become a hot research topic in the medical field in recent years, with
enormous potential for treating a variety of diseases. In particular, bone marrow …
enormous potential for treating a variety of diseases. In particular, bone marrow …
Limitations and potential strategies of immune checkpoint blockade in age-related neurodegenerative disorders
NN Lasheen, S Allam, A Elgarawany, DW Aswa… - The Journal of …, 2024 - Springer
Neurological disorders such as Alzheimer's disease (AD), and Parkinson's disease (PD)
have no disease-modifying treatments, resulting in a global dementia crisis that affects more …
have no disease-modifying treatments, resulting in a global dementia crisis that affects more …