Understanding the targets and mechanisms of human immunity to malaria caused by
Plasmodium falciparum is crucial for advancing effective vaccines and developing tools for …

After a successful invasion, malaria parasite Plasmodium falciparum extensively remodels
the infected erythrocyte cellular architecture, conferring cytoadhesive properties to the …

Cerebral malaria is a deadly outcome of infection by Plasmodium falciparum, occurring
when parasite-infected erythrocytes accumulate in the brain. These erythrocytes display …

Variant surface antigens play an important role in Plasmodium falciparum malaria
pathogenesis and in immune evasion by the parasite. Although most work to date has …

Coevolution of humans and malaria parasites has generated an intricate balance between
the immune system of the host and virulence factors of the parasite, equilibrating maximal …

The clinical manifestations of severe malaria are several and occur in different anatomical
sites. Both parasite-and host-related factors contribute to the pathogenicity of the severe …

Infections with Plasmodium falciparum and Plasmodium vivax cause over 600,000 deaths
each year, concentrated in Africa and in young children, but much of the world's population …

Over the past decade, there has been a transformation in the portfolio of medicines to
combat malaria. New fixed-dose artemisinin combination therapy is available, with four …

African swine fever virus (ASFV) is the cause of African swine fever (ASF), a devastating
disease that affects domestic pigs and wild boar and is currently responsible for the largest …

The ABO blood group influences susceptibility to severe Plasmodium falciparum malaria.
Recent evidence indicates that the protective effect of group O operates by virtue of reduced …