Many variant proteins encoded by Plasmodium-specific multigene families are exported into
red blood cells (RBC). P. falciparum-specific variant proteins encoded by the var, stevor and …

The ability of the intraerythrocytic Plasmodium spp. to form spontaneous rosettes with
uninfected red blood cells (URBCs) has been observed in the medically important malaria …

Malaria remains a major cause of mortality in African children, with no adjunctive treatments
currently available to ameliorate the severe clinical forms of the disease. Rosetting, the …

The intracellular malaria parasites extensively modify host erythrocytes to allow nutrient
uptake, ensure homeostasis, and evade the host's immune response. To achieve this, the …

Sequence diversity in pathogen antigens is an obstacle to the development of interventions
against many infectious diseases. In malaria caused by Plasmodium falciparum, the PfEMP1 …

Adhesion interactions between Plasmodium falciparum-infected erythrocytes (IE) and
human cells underlie the pathology of severe malaria. IE cytoadhere to microvascular …

Malaria, caused by apicomplexan parasite, is an old disease and continues to be a major
public health threat in many countries. This article aims to present different aspects of …

Severe malaria remains a major cause of global mortality. The innate immune response to
infection is a key determinant of malaria severity and outcome. The complement system …

PfEMP1 is a family of cytoadhesive surface antigens expressed on erythrocytes infected with
Plasmodium falciparum, the parasite that causes the most severe form of malaria. These …

It is well established that pregnant women are at an increased risk of Plasmodium
falciparum infection when compared to non-pregnant individuals and limited …