Passive stiffness of airway smooth muscle: the next target for improving airway distensibility and treatment for asthma?
CY Seow - Pulmonary pharmacology & therapeutics, 2013 - Elsevier
Reduced airway distensibility due to increased airway stiffness is a characteristic of asthma.
Airway stiffness is determined by the property and structural organization of the various …
Airway stiffness is determined by the property and structural organization of the various …
Differentiation of quantitative CT imaging phenotypes in asthma versus COPD
Introduction Quantitative CT (QCT) imaging-based metrics have quantified disease
alterations in asthma and chronic obstructive pulmonary disease (COPD), respectively. We …
alterations in asthma and chronic obstructive pulmonary disease (COPD), respectively. We …
[HTML][HTML] Changes in airway diameter and mucus plugs in patients with asthma exacerbation
Y Yoshida, Y Takaku, Y Nakamoto, N Takayanagi… - PLoS …, 2020 - journals.plos.org
Background Airway obstruction due to decreased airway diameter and increased incidence
of mucus plugs has not been directly observed in asthma exacerbation. We studied the …
of mucus plugs has not been directly observed in asthma exacerbation. We studied the …
Heterogeneity of airway wall dimensions in humans: a critical determinant of lung function in asthmatics and nonasthmatics
Airway remodeling, a key feature of asthma, alters every layer of the airway wall but most
strikingly the airway smooth muscle (ASM) layer. Airway remodeling in asthmatics …
strikingly the airway smooth muscle (ASM) layer. Airway remodeling in asthmatics …
Airway dimensions in asthma and COPD in high resolution computed tomography: can we see the difference?
J Kosciuch, R Krenke, K Gorska, M Zukowska… - Respiratory …, 2013 - rc.rcjournal.com
BACKGROUND: Airway remodeling in asthma and COPD results in bronchial wall
thickening. The thickness of the bronchial wall can be measured in high-resolution …
thickening. The thickness of the bronchial wall can be measured in high-resolution …
[HTML][HTML] Inflammatory cytokines and T-lymphocyte subsets in serum and sputum in patients with bronchial asthma and chronic obstructive pulmonary disease
Y Bai, Q Zhou, Q Fang, L Song… - Medical Science Monitor …, 2019 - ncbi.nlm.nih.gov
Background It can be difficult to distinguish between bronchial asthma and chronic
obstructive pulmonary disease (COPD) clinically, although these conditions are associated …
obstructive pulmonary disease (COPD) clinically, although these conditions are associated …
Expression patterns of serum miR‐27a‐3p and activating transcription factor 3 in children with bronchial asthma and their correlations with airway inflammation
J Wang, L Yang, P Sun, C Guo, Y Jin… - The Clinical …, 2023 - Wiley Online Library
Introduction Bronchial asthma (BA) is a heterogeneous disease characterized by chronic
airway inflammation. This study investigated the serum miR‐27a‐3p/activating transcription …
airway inflammation. This study investigated the serum miR‐27a‐3p/activating transcription …
[HTML][HTML] Discriminating dominant computed tomography phenotypes in smokers without or with mild COPD
Background Finding phenotypes within COPD patients may prove imperative for optimizing
treatment and prognosis. We hypothesized that it would be possible to discriminate …
treatment and prognosis. We hypothesized that it would be possible to discriminate …
Semiautomated segmentation and analysis of airway lumen in pediatric patients using ultra short echo time MRI
Rationale and Objectives Ultra short echo time (UTE) magnetic resonance imaging (MRI)
pulse sequences have shown promise for airway assessment, but the feasibility and …
pulse sequences have shown promise for airway assessment, but the feasibility and …
[HTML][HTML] Comparison of endobronchial ultrasound and high resolution computed tomography as tools for airway wall imaging in asthma and chronic obstructive …
K Gorska, P Korczynski, M Mierzejewski, J Kosciuch… - Respiratory …, 2016 - Elsevier
Introduction Airway remodeling in asthma and chronic obstructive pulmonary disease
(COPD) results in bronchial wall thickening. Bronchial wall thickness (BWT) can be …
(COPD) results in bronchial wall thickening. Bronchial wall thickness (BWT) can be …