Cervical cancer screening: past, present, and future

SL Bedell, LS Goldstein, AR Goldstein… - Sexual medicine …, 2020 - academic.oup.com
Introduction Cervical cancer is the leading cause of cancer deaths in women in the
developing world. New technologies have been developed to allow for more rapid, cost …

Carcinogenic human papillomavirus infection

M Schiffman, J Doorbar, N Wentzensen… - Nature reviews Disease …, 2016 - nature.com
Infections with human papillomavirus (HPV) are common and transmitted by direct contact.
Although the great majority of infections resolve within 2 years, 13 phylogenetically related …

The vaginal microbiota associates with the regression of untreated cervical intraepithelial neoplasia 2 lesions

A Mitra, DA MacIntyre, G Ntritsos, A Smith… - Nature …, 2020 - nature.com
Emerging evidence suggests associations between the vaginal microbiota (VMB)
composition, human papillomavirus (HPV) infection, and cervical intraepithelial neoplasia …

The vaginal microbiota, human papillomavirus infection and cervical intraepithelial neoplasia: what do we know and where are we going next?

A Mitra, DA MacIntyre, JR Marchesi, YS Lee… - Microbiome, 2016 - Springer
The vaginal microbiota plays a significant role in health and disease of the female
reproductive tract. Next-generation sequencing techniques based upon the analysis of …

American Cancer Society, American Society for Colposcopy and Cervical Pathology, and American Society for Clinical Pathology screening guidelines for the …

D Saslow, D Solomon, HW Lawson… - American journal of …, 2012 - academic.oup.com
An update to the American Cancer Society (ACS) guideline regarding screening for the early
detection of cervical precancerous lesions and cancer is presented. The guidelines are …

A study of type-specific HPV natural history and implications for contemporary cervical cancer screening programs

M Demarco, N Hyun, O Carter-Pokras… - …, 2020 - thelancet.com
Background HPV testing is replacing cytology for cervical cancer screening because of
greater sensitivity and superior reassurance following negative tests for the dozen HPV …

Characterization of cervico-vaginal microbiota in women developing persistent high-risk Human Papillomavirus infection

M Di Paola, C Sani, AM Clemente, A Iossa, E Perissi… - Scientific reports, 2017 - nature.com
Abstract Changes in cervico-vaginal microbiota with Lactobacillus depletion and increased
microbial diversity facilitate human papillomavirus (HPV) infection and might be involved in …

Human papillomavirus testing in the prevention of cervical cancer

M Schiffman, N Wentzensen… - Journal of the …, 2011 - academic.oup.com
Strong evidence now supports the adoption of cervical cancer prevention strategies that
explicitly focus on persistent infection with the causal agent, human papillomavirus (HPV) …

Epidemiology and natural history of human papillomavirus infections and type-specific implications in cervical neoplasia

FX Bosch, AN Burchell, M Schiffman, AR Giuliano… - Vaccine, 2008 - Elsevier
Worldwide human papillomavirus (HPV) prevalence in women with normal cytology at any
given point in time is approximately 10% indicating that HPV is one of the most common …

Longitudinal study of human papillomavirus persistence and cervical intraepithelial neoplasia grade 2/3: critical role of duration of infection

AC Rodríguez, M Schiffman, R Herrero… - Journal of the …, 2010 - academic.oup.com
Background The natural history of human papillomavirus (HPV) infections in older women is
critical for preventive strategies, including vaccination and screening intervals, but is poorly …