Gastric cancer is a common malignancy with a poor prognosis, and surgical treatment
remains the first-line approach to treatment to provide a cure. Despite advances in surgical …

Background Accurate prediction of treatment response to neoadjuvant chemotherapy
(NACT) in individual patients with locally advanced gastric cancer (LAGC) is essential for …

Gastrectomy with D2 lymph node dissection has become the global standard procedure for
locally advanced gastric cancer to maximally reduce locoregional recurrence. In East Asia …

Chemotherapy is the standard care for patients with gastric cancer (GC); however,
resistance to existing drugs has limited its success. The persistence of cancer stem cells …

Importance Apatinib is a novel treatment option for chemotherapy-refractory advanced
gastric cancer (GC), but it has not been evaluated in patients with locally advanced GC …

Background Neoadjuvant chemotherapy is a promising treatment option for potential
resectable gastric cancer, but patients' responses vary. We aimed to develop and validate a …

Gastric cancer (GC) is a serious affliction worldwide and remains to be the fourth most
common cancer with poor prognosis, especially in advanced stage. Chemotherapy is one of …

Background Pathologic complete response of a primary tumor (ypT0) after preoperative
therapy is associated with improved overall survival (OS). However, whether other variables …

Objectives Exploring the efficacy and safety of perioperative chemotherapy on patients with
AGC at different clinical and pathological stages. Methods A phase III randomized …

Background Patients with N3 stage nasopharyngeal carcinoma (NPC) are at high risk for
treatment failure. This study aims to assess the efficacy of maintenance chemotherapy (MC) …