B-cell-specific Moloney murine leukemia virus integration region 1 (Bmi-1, also known as
RNF51 or PCGF4) is one of the important members of the PcG gene family, and is involved …

Polycomb group genes (PcGs) are epigenetic effectors, essential for stem cell self-renewal
and pluripotency. Two main Polycomb repressive complexes (PRC1, PRC2) mediate gene …

MicroRNAs (miRNAs) are short noncoding RNAs that play crucial roles in tumorigenesis and
tumor progression. Melanoma is the most aggressive skin cancer that is resistant or rapidly …

Aims Hsa_circ_0007534 has been reported to be a novel cancer-related circRNA affecting
multiple cancers. However, little is known about the role of hsa_circ_0007534 in cervical …

Background Cholangiocarcinoma (CCA) is a class of malignant tumors originating from bile
duct epithelial cells. Due to difficult early diagnosis and limited treatment, the prognosis of …

Background The purpose of present study was to examine the expression of cancer stem
cell marker Bmi-1 in breast cancer tissue and to evaluate the clinical implication of Bmi-1 …

Neuroblastoma (NB) is a paediatric cancer with noteworthy heterogeneity ranging from
spontaneous regression to high-risk forms that are characterised by cancer relapse and the …

Introduction Cervical cancer remains a leading cause of cancer-related deaths in women in
spite of screening and vaccination programs. The current treatment strategies including …

Endometrial adenocarcinoma is one of the most common types of gynecological
malignancies and its incidence and mortality rates are increasing. Due to tumor recurrence …

Previous studies have shown that wild-type human telomerase reverse transcriptase
(hTERT) protein can functionally replace the human papillomavirus type 16 (HPV-16) E6 …