[HTML][HTML] Oxidative stress and inflammation in osteoarthritis pathogenesis: Role of polyphenols

MY Ansari, N Ahmad, TM Haqqi - Biomedicine & pharmacotherapy, 2020 - Elsevier
Osteoarthritis (OA) is the most prevalent joint degenerative disease leading to irreversible
structural and functional changes in the joint and is a major cause of disability and reduced …

[HTML][HTML] Nutraceutical approach to chronic osteoarthritis: from molecular research to clinical evidence

A Colletti, AFG Cicero - International journal of molecular sciences, 2021 - mdpi.com
Osteoarthritis (OA) is a degenerative inflammatory condition of the joint cartilage that
currently affects approximately 58 million adults in the world. It is characterized by pain …

The glucosinolates and their bioactive derivatives in Brassica: a review on classification, biosynthesis and content in plant tissues, fate during and after processing …

K Sikorska-Zimny, L Beneduce - Critical Reviews in Food Science …, 2021 - Taylor & Francis
The present study is a systematic review of the scientific literature reporting content,
composition and biosynthesis of glucosinolates (GLS), and their derivative compounds in …

Isoliquiritigenin, a potential therapeutic agent for treatment of inflammation-associated diseases

Z Chen, W Ding, X Yang, T Lu, Y Liu - Journal of ethnopharmacology, 2023 - Elsevier
Ethnopharmacological relevance Licorice is a medicinal herb with a 2000-year history of
applications in traditional Chinese medicine. Isoliquiritigenin (ISL) is a bioactive chalcone …

[HTML][HTML] Nutraceutical activity in osteoarthritis biology: a focus on the nutrigenomic role

S D'Adamo, S Cetrullo, V Panichi, E Mariani… - Cells, 2020 - mdpi.com
Osteoarthritis (OA) is a disease associated to age or conditions that precipitate aging of
articular cartilage, a post-mitotic tissue that remains functional until the failure of major …

[HTML][HTML] Emerging natural-product-based treatments for the management of osteoarthritis

ML Pérez-Lozano, A Cesaro, M Mazor, E Esteve… - Antioxidants, 2021 - mdpi.com
Osteoarthritis (OA) is a complex degenerative disease in which joint homeostasis is
disrupted, leading to synovial inflammation, cartilage degradation, subchondral bone …

The effect of kaempferol and apigenin on allogenic synovial membrane-derived stem cells therapy in knee osteoarthritic male rats

F Estakhri, MR Panjehshahin, N Tanideh, R Gheisari… - The Knee, 2020 - Elsevier
Background Based on the anti-inflammatory and anti-oxidant properties of kaempferol and
apigenin, we hypothesized that co-injection of these phytochemicals would increase the …

Sambucus nigra flower and berry extracts for food and therapeutic applications: effect of gastrointestinal digestion on in vitro and in vivo bioactivity and toxicity

P Ferreira-Santos, A Nogueira, CMR Rocha… - Food & Function, 2022 - pubs.rsc.org
The bioavailability of natural compounds should be assessed through different perspectives.
Studying the behaviour of the extracts after digestion is often overlooked but is crucial for …

[HTML][HTML] Sulforaphane protects against oxidative stress‑induced apoptosis via activating SIRT1 in mouse osteoarthritis

M Chen, L Huang, Y Lv, L Li… - Molecular Medicine …, 2021 - spandidos-publications.com
Osteoarthritis (OA), the most common form of human joint disease, is characterized by
progressive degeneration of the articular cartilage, synovitis and subchondral osteoporosis …

[HTML][HTML] NRF2-related epigenetic modifications in cardiac and vascular complications of diabetes mellitus

J Wang, M Xiao, J Wang, S Wang, J Zhang… - Frontiers in …, 2021 - frontiersin.org
Diabetes mellitus (DM) is a highly prevalent chronic disease that is accompanied with
serious complications, especially cardiac and vascular complications. Thus, there is an …