The rationale for the renal denervation treatment of severe, drug-resistant essential
hypertension remains valid, but the field is now at a procedural watershed. With the …

The prevalence of hypertension rises with age to approximately two out of three adults over
the age of 60 in the United States. Although the mechanisms underlying age-related …

Renal denervation (RDN) is a treatment option for patients with hypertension resistant to
conventional therapy. Clinical trials have demonstrated variable benefit. To understand the …

Background—Electric stimulation has been proved to be available to monitor the efficacy of
renal denervation (RDN). This study was to evaluate the effectiveness of high-frequency …

The aim of this study was to investigate alterations in the intrarenal blood pressure (BP)
regulation system after renal denervation (RDN) guided by renal nerve stimulation (RNS) …

Objective: The RADIANCE-HTN SOLO trial demonstrated a greater reduction in daytime
ambulatory SBP at 2 months by endovascular ultrasound renal denervation than sham …

Chronic kidney disease (CKD) represents a significant and escalating global health
challenge, with morbidity and mortality rates rising steadily. Evidence increasingly implicates …

Autonomic nervous system plays a crucial role in maintaining and regulating vessel tension.
Renal denervation (RDN) may induce renal artery vasodilation by damaging renal …

Background Age-related alterations in renal sodium handling affect blood pressure (BP). We
aimed to clarify whether the pressure-natriuresis response changes with age, leading to BP …

BACKGROUND The large animal model of arterial hypertension is very valuable to test the
antihypertensive drugs and devices. We characterized a novel swine model of spontaneous …