Epithelial barrier hypothesis: effect of the external exposome on the microbiome and epithelial barriers in allergic disease

Z Celebi Sozener, B Ozdel Ozturk, P Cerci, M Turk… - Allergy, 2022 - Wiley Online Library
Environmental exposure plays a major role in the development of allergic diseases. The
exposome can be classified into internal (eg, aging, hormones, and metabolic processes) …

Molecular mechanisms of oxidative stress in asthma

C Michaeloudes, H Abubakar-Waziri, R Lakhdar… - Molecular aspects of …, 2022 - Elsevier
The lungs are exposed to reactive oxygen species oxygen (ROS) produced as a result of
inhalation of oxygen, as well as smoke and other air pollutants. Cell metabolism and the …

Overview of the mechanisms of oxidative stress: impact in inflammation of the airway diseases

GD Albano, RP Gagliardo, AM Montalbano, M Profita - Antioxidants, 2022 - mdpi.com
Inflammation of the human lung is mediated in response to different stimuli (eg, physical,
radioactive, infective, pro-allergenic or toxic) such as cigarette smoke and environmental …

[HTML][HTML] Exposure to outdoor and indoor air pollution and risk of overweight and obesity across different life periods: A review

X Shi, Y Zheng, H Cui, Y Zhang, M Jiang - … and environmental safety, 2022 - Elsevier
Due to the highly evolved industrialization and modernization, air quality has deteriorated in
most countries. As reported by the World Health Organization (WHO), air pollution is now …

Cellular compartmentalization, glutathione transport and its relevance in some pathologies

H Vázquez-Meza, MM Vilchis-Landeros… - Antioxidants, 2023 - mdpi.com
Reduced glutathione (GSH) is the most abundant non-protein endogenous thiol. It is a
ubiquitous molecule produced in most organs, but its synthesis is predominantly in the liver …

Ferroptosis induced by pollutants: an emerging mechanism in environmental toxicology

L Yang, X Cai, R Li - Environmental Science & Technology, 2024 - ACS Publications
Environmental pollutants have been recognized for their ability to induce various adverse
outcomes in both the environment and human health, including inflammation, apoptosis …

Bibliometric analysis of the inflammasome and pyroptosis in brain

Y Chen, Y Li, L Guo, J Hong, W Zhao, X Hu… - Frontiers in …, 2021 - frontiersin.org
Background: Considering the pivotal role of inflammasome/pyroptosis in biological function,
we visually analyzed the research hotspots of inflammasome/pyroptosis related to the brain …

[HTML][HTML] Short-term exposure to ozone and cause-specific mortality risks and thresholds in China: Evidence from nationally representative data, 2013-2018

C Chen, T Li, Q Sun, W Shi, MZ He, J Wang, J Liu… - Environment …, 2023 - Elsevier
Background Ambient ozone pollution is steadily increasing and becoming a major
environmental risk factor contributing to the global disease burden. Although the association …

Cardiovascular diseases crossroads: cGAS-STING signaling and disease progression

MS Khan, SU Khan, SU Khan, M Suleman… - Current Problems in …, 2023 - Elsevier
It is now widely accepted that inflammation is critical in cardiovascular diseases (CVD).
Here, studies are being conducted on how cyclic GMP-AMP synthase (cGAS), a component …

Endoplasmic reticulum stress and oxidative stress in inflammatory diseases

Y Tang, X Zhou, T Cao, E Chen, Y Li, W Lei… - DNA and Cell …, 2022 - liebertpub.com
Endoplasmic reticulum (ER) stress and oxidative stress (OS) are often related states in cells
as part of normal physiology but more frequently manifested in the pathophysiology of many …