Epithelial barrier hypothesis: effect of the external exposome on the microbiome and epithelial barriers in allergic disease
Environmental exposure plays a major role in the development of allergic diseases. The
exposome can be classified into internal (eg, aging, hormones, and metabolic processes) …
exposome can be classified into internal (eg, aging, hormones, and metabolic processes) …
Molecular mechanisms of oxidative stress in asthma
C Michaeloudes, H Abubakar-Waziri, R Lakhdar… - Molecular aspects of …, 2022 - Elsevier
The lungs are exposed to reactive oxygen species oxygen (ROS) produced as a result of
inhalation of oxygen, as well as smoke and other air pollutants. Cell metabolism and the …
inhalation of oxygen, as well as smoke and other air pollutants. Cell metabolism and the …
Overview of the mechanisms of oxidative stress: impact in inflammation of the airway diseases
GD Albano, RP Gagliardo, AM Montalbano, M Profita - Antioxidants, 2022 - mdpi.com
Inflammation of the human lung is mediated in response to different stimuli (eg, physical,
radioactive, infective, pro-allergenic or toxic) such as cigarette smoke and environmental …
radioactive, infective, pro-allergenic or toxic) such as cigarette smoke and environmental …
[HTML][HTML] Exposure to outdoor and indoor air pollution and risk of overweight and obesity across different life periods: A review
X Shi, Y Zheng, H Cui, Y Zhang, M Jiang - … and environmental safety, 2022 - Elsevier
Due to the highly evolved industrialization and modernization, air quality has deteriorated in
most countries. As reported by the World Health Organization (WHO), air pollution is now …
most countries. As reported by the World Health Organization (WHO), air pollution is now …
Cellular compartmentalization, glutathione transport and its relevance in some pathologies
H Vázquez-Meza, MM Vilchis-Landeros… - Antioxidants, 2023 - mdpi.com
Reduced glutathione (GSH) is the most abundant non-protein endogenous thiol. It is a
ubiquitous molecule produced in most organs, but its synthesis is predominantly in the liver …
ubiquitous molecule produced in most organs, but its synthesis is predominantly in the liver …
Ferroptosis induced by pollutants: an emerging mechanism in environmental toxicology
L Yang, X Cai, R Li - Environmental Science & Technology, 2024 - ACS Publications
Environmental pollutants have been recognized for their ability to induce various adverse
outcomes in both the environment and human health, including inflammation, apoptosis …
outcomes in both the environment and human health, including inflammation, apoptosis …
Bibliometric analysis of the inflammasome and pyroptosis in brain
Y Chen, Y Li, L Guo, J Hong, W Zhao, X Hu… - Frontiers in …, 2021 - frontiersin.org
Background: Considering the pivotal role of inflammasome/pyroptosis in biological function,
we visually analyzed the research hotspots of inflammasome/pyroptosis related to the brain …
we visually analyzed the research hotspots of inflammasome/pyroptosis related to the brain …
[HTML][HTML] Short-term exposure to ozone and cause-specific mortality risks and thresholds in China: Evidence from nationally representative data, 2013-2018
Background Ambient ozone pollution is steadily increasing and becoming a major
environmental risk factor contributing to the global disease burden. Although the association …
environmental risk factor contributing to the global disease burden. Although the association …
Cardiovascular diseases crossroads: cGAS-STING signaling and disease progression
It is now widely accepted that inflammation is critical in cardiovascular diseases (CVD).
Here, studies are being conducted on how cyclic GMP-AMP synthase (cGAS), a component …
Here, studies are being conducted on how cyclic GMP-AMP synthase (cGAS), a component …
Endoplasmic reticulum stress and oxidative stress in inflammatory diseases
Y Tang, X Zhou, T Cao, E Chen, Y Li, W Lei… - DNA and Cell …, 2022 - liebertpub.com
Endoplasmic reticulum (ER) stress and oxidative stress (OS) are often related states in cells
as part of normal physiology but more frequently manifested in the pathophysiology of many …
as part of normal physiology but more frequently manifested in the pathophysiology of many …