Heat shock proteins (Hsps) are overexpressed in a wide range of human cancers and are
implicated in tumor cell proliferation, differentiation, invasion, metastasis, death, and …

Molecular chaperones, many of which are heat-shock proteins (HSPs), are an important
class of molecules with various functions. Pathological conditions in which chaperones …

Background Hsp90-beta and annexin A1 were investigated as prognostic factors because of
their apparent association with tumorigenesis. However, the effect of Hsp90-beta and …

Background Breast cancer is the most common malignancy among women worldwide in
terms of incidence and mortality. About 10% of North American women will be diagnosed …

Abstract Background Heat shock proteins (HSPs) are ubiquitous, highly conserved proteins
across all the species and play essential roles in maintaining protein stability within the cells …

Cellular stress response and apoptosis are two highly conserved mechanisms for
maintaining homeostasis. Hsp60 and Hsp90 have been shown to play pro-and anti …

Gastric cancer is the second most fatal common form of cancer. The crosstalk among
signalling pathways that results in the acceleration of epithelial to mesenchymal transition …

Abstract Heat shock protein 90 (Hsp90) has been demonstrated to protect oncogenic
variants of signalling molecules from degradation and may consequently serve as a …

Patients with lung cancer at the same stage may have markedly different overall outcome
and a lack of specific biomarker to predict lung cancer outcome. Heat-shock protein 90 β …

One of many hypotheses of psoriasis pathogenesis supposes an overexpression of heat
shock proteins (Hsps) in different skin layers and systemic immunologic response to them …