ABSTRACT Introduction: Fibroblast growth factors (FGFs) are key mitogens in tissue
homeostasis and cancer. FGF2 regulates self-renewal of multiple stem-cell types, is widely …

Cell migrations are diverse. They constitutemajor morphogenetic driving forces during
embryogenesis, but they contribute also to the loss of tissue homeostasis and cancer …

Whether membrane-anchored PD-L1 homodimerizes in living cells is controversial. The
biological significance of the homodimer waits to be expeditiously explored. However …

Receptor tyrosine kinases (RTKs) are cell surface receptors which control cell growth and
differentiation, and play important roles in tumorigenesis. Despite decades of RTK research …

Tropomyosin-receptor kinases (TRKs) are essential for the development of the nervous
system. The molecular mechanism of TRKA activation by its ligand nerve growth factor …

Heparin plays a significant role in wound healing and tissue regeneration applications,
through stabilization of fibroblast growth factors (FGF). Risks associated with batch‐to‐batch …

Fibroblast growth factor receptors (FGFRs) are integral membrane proteins that transmit
signals through the plasma membrane. FGFRs signaling needs to be precisely adjusted as …

Breast cancer (BC) is the most common malignancy and second only to lung cancer in terms
of mortality in women. Despite the incredible progress made in this field, metastatic breast …

The epidermal growth factor receptor (EGFR) family is an important class of receptor tyrosine
kinases, mediating a variety of cellular responses in normal biological processes and in …

The development of pharmacological and biological inhibitors of receptor tyrosine kinases
(RTKs) has changed the treatment paradigm of several neoplastic diseases. However, the …