Metabolomics: small molecules that matter more
BC Muthubharathi, T Gowripriya, K Balamurugan - Molecular omics, 2021 - pubs.rsc.org
Metabolomics, an analytical study with high-throughput profiling, helps to understand
interactions within a biological system. Small molecules, called metabolites or metabolomes …
interactions within a biological system. Small molecules, called metabolites or metabolomes …
The role of vitamins in neurodegenerative disease: An update
Acquiring the recommended daily allowance of vitamins is crucial for maintaining
homeostatic balance in humans and other animals. A deficiency in or dysregulation of …
homeostatic balance in humans and other animals. A deficiency in or dysregulation of …
Gut microbiota and metabolome alterations associated with Parkinson's disease
Parkinson's disease is a neurodegenerative disorder characterized by the accumulation of
intracellular aggregates of misfolded alpha-synuclein along the cerebral axis. Several …
intracellular aggregates of misfolded alpha-synuclein along the cerebral axis. Several …
[HTML][HTML] ESPEN micronutrient guideline
MM Berger, A Shenkin, A Schweinlin, K Amrein… - Clinical Nutrition, 2022 - Elsevier
Background Trace elements and vitamins, named together micronutrients (MNs), are
essential for human metabolism. Recent research has shown the importance of MNs in …
essential for human metabolism. Recent research has shown the importance of MNs in …
Cerebral deficiency of vitamin B5 (d-pantothenic acid; pantothenate) as a potentially-reversible cause of neurodegeneration and dementia in sporadic Alzheimer's …
J Xu, S Patassini, P Begley, S Church… - Biochemical and …, 2020 - Elsevier
Alzheimer's disease (AD) is the most common cause of age-related neurodegeneration and
dementia, and there are no available treatments with proven disease-modifying actions. It is …
dementia, and there are no available treatments with proven disease-modifying actions. It is …
The pathophysiological role of CoA
A Czumaj, S Szrok-Jurga, A Hebanowska… - International Journal of …, 2020 - mdpi.com
The importance of coenzyme A (CoA) as a carrier of acyl residues in cell metabolism is well
understood. Coenzyme A participates in more than 100 different catabolic and anabolic …
understood. Coenzyme A participates in more than 100 different catabolic and anabolic …
Gut microbiota-derived vitamins–underrated powers of a multipotent ally in psychiatric health and disease
Despite the well-established roles of B-vitamins and their deficiencies in health and disease,
there is growing evidence indicating a key role of those nutrients in functions of the central …
there is growing evidence indicating a key role of those nutrients in functions of the central …
Immunoassays for the rapid detection of pantothenic acid in pharmaceutical and food products
Pharmaceutical and food products are fortified with pantothenic acid (PA) to address
potential deficiency. Therefore, its fast, reliable, and accurate detection is of great …
potential deficiency. Therefore, its fast, reliable, and accurate detection is of great …
UPLC-MS-based urine nontargeted metabolic profiling identifies dysregulation of pantothenate and CoA biosynthesis pathway in diabetic kidney disease
T Ma, T Liu, P Xie, S Jiang, W Yi, P Dai, X Guo - Life sciences, 2020 - Elsevier
Aims Diabetic kidney disease (DKD) is a major prevalent chronic microvascular
complication of type 2 diabetes (T2D). However, the present diagnostic indicators have …
complication of type 2 diabetes (T2D). However, the present diagnostic indicators have …
Multi-regional alterations in glucose and purine metabolic pathways in the Parkinson's disease dementia brain
M Scholefield, SJ Church, G Taylor, D Knight… - npj Parkinson's …, 2023 - nature.com
Parkinson's disease (PD) is one of the most common neurodegenerative diseases, most
commonly characterised by motor dysfunction, but also with a high prevalence of cognitive …
commonly characterised by motor dysfunction, but also with a high prevalence of cognitive …