Accumulated evidence strongly indicates that oxidative stress, characterized by an
imbalance between reactive oxygen species (ROS) production and antioxidants in favor of …

Cellular metabolism in hematopoietic stem cells (HSCs) is an area of intense research
interest, but the metabolic requirements of HSCs and their adaptations to their niches during …

Dormant hematopoietic stem cells (dHSCs) are atop the hematopoietic hierarchy. The
molecular identity of dHSCs and the mechanisms regulating their maintenance or exit from …

Accumulating evidence indicates that intracellular reactive oxygen species (ROS)
production is highly involved in bone homeostasis by intervening osteoclast or osteoblast …

Hematopoietic stem cells (HSCs) possess two important properties such as self-renewal and
differentiation. These properties of HSCs are maintained through hematopoiesis. This …

Abstract Background In the American population, the relationship between the triglyceride-
glucose (TyG) index and TYG combined with indicators of obesity and cardiovascular …

Many tissues and organ systems in metazoans have the intrinsic capacity to regenerate,
which is driven and maintained largely by tissue-resident somatic stem cell populations …

Despite the importance of stem cells in plant and animal development, the common
mechanisms of stem cell maintenance in both systems have remained elusive. Recently, the …

Iron, an indispensable element for life, is involved in all kinds of important physiological
activities. Iron promotes cell growth and proliferation, but it also causes oxidative stress …

Hematopoietic stem cells (HSCs) rely on complex regulatory networks to preserve stemness.
Due to the scarcity of HSCs, technical challenges have limited our insights into the interplay …