Endothelium is a site of metabolic activity and has a major reservoir of multipotent stem cells.
It plays a vital role in the vascular physiological, pathophysiological and reparative …

Introduction Male and female sexual dysfunction (SD) is considered a multifactorial
condition. Numerous studies have shown the involvement of inflammatory processes in this …

Vascular permeability is temporarily heightened during inflammation, but excessive
inflammation‐associated microvascular leakage can be detrimental, as evidenced in the …

Vascular hyperpermeability is a complication of hemorrhagic shock. Pericytes (PCs) are a
group of mural cells surrounded by microvessels that are located on the basolateral side of …

Aberrant immune responses, including hyperresponsiveness to Toll-like receptor (TLR)
ligands, underlie acute respiratory distress syndrome (ARDS). Type I interferons confer …

Several human diseases, include cancer and stroke are characterized by changes in
immune system activation and vascular contractility. However, the mechanistic foundation of …

Neutrophils are heterogeneous and plastic, with the ability to polarize from antitumour to
protumour phenotype and modulate tumour microenvironment components. While some …

Although cardiovascular diseases (CVD) are the leading cause of global mortality, there is a
lack of therapies that target and revert underlying pathological processes. Mitochondrial …

Cardiovascular disease poses a significant threat to individuals with kidney disease,
including those affected by acute kidney injury (AKI). In the short term, AKI has several …

Cell death has long been a characteristic phenotype of organ damage in hypertension, and
recently, leaky gut has been revealed as a novel hypertensive phenotype. However, despite …