Mechanisms of I/R-induced endothelium-dependent vasodilator dysfunction

RJ Korthuis - Advances in Pharmacology, 2018 - Elsevier
Abstract Ischemia/reperfusion (I/R) induces leukocyte/endothelial cell adhesive interactions
(LECA) in postcapillary venules and impaired endothelium-dependent, NO-mediated …

Increase in soluble protein oligomers triggers the innate immune system promoting inflammation and vascular dysfunction in the pathogenesis of sepsis

A Komic, P Martinez-Quinones, CG McCarthy… - Clinical …, 2018 - portlandpress.com
Sepsis is a profoundly morbid and life-threatening condition, and an increasingly alarming
burden on modern healthcare economies. Patients with septic shock exhibit persistent …

The effect of Wenxin Keli on the mRNA expression profile of rabbits with myocardial infarction

M Zheng, Z Liu, N Liu, C Hou, J Pu… - Evidence‐Based …, 2016 - Wiley Online Library
Aims. The molecular mechanisms of Chinese traditional medicine Wenxin Keli (WXKL) were
unknown. This study was aimed at exploring the effects of WXKL on the gene expression …

PAMPs and DAMPs in sepsis: a review of their molecular features and potential clinical implications

S Cicchinelli, G Pignataro, S Gemma… - International Journal of …, 2024 - mdpi.com
Sepsis is a serious organ dysfunction caused by a dysregulated immune host reaction to a
pathogen. The innate immunity is programmed to react immediately to conserved molecules …

[HTML][HTML] Basophil activation through TLR2 and TLR4 signaling pathways

M Alkan, F Sayes, A Ramadan… - AIMS Allergy and …, 2018 - aimspress.com
Basophils are effector cells that respond to protease allergens and parasites, thus
contributing to allergic inflammation and Th2 differentiation. However, the molecular …

Pink1-mediated mitophagy in the endothelium releases proteins encoded by mitochondrial DNA and activates neutrophil responses

P Gajwani, L Wang, S Srivastava, Z Ye, YM Kim… - bioRxiv, 2022 - biorxiv.org
Given their ancient evolutionary origins, eukaryotic mitochondria possess multiple vestiges
of their prokaryotic ancestors. One such factor is the N-terminal formylation of proteins …

[PDF][PDF] 脓毒症患者血浆可溶性晚期糖基化终末产物受体水平与心功能的关系

张娈娈, 王奇坤, 陈德, 周荣 - 中国循环杂志, 2016 - nccd.org.cn
摘要目的: 通过监测脓毒症患者血浆可溶性晚期糖基化终末产物受体(sRAGE), B 型利钠肽(BNP)
水平的关系, 探讨血浆sRAGE 水平与脓毒症患者心功能的关系. 方法: 选择2014-01 至2015-06 …

The Pathogenetic Role of DAMPs in Severe Infectious Diseases

WG Land - Damage-Associated Molecular Patterns in Human …, 2023 - Springer
This fourth chapter of the “Infection” Part begins with an overview of reports on the various
subclasses of activating damage-associated molecular patterns (DAMPs) and suppressing …

Mécanismes immunologiques post-traumatiques: de l'attrition tissulaire à la défaillance d'organes

PO Ludes, E Noll, J Pottecher - Anesthésie & Réanimation, 2020 - Elsevier
Résumé Le traumatisme sévère reste grevé d'une mortalité et d'une morbidité
particulièrement élevées, au point de constituer la première cause d'années de vie perdues …

Identification des cibles antigéniques d'origine mitochondriale, reconnues par les autoanticorps dans le lupus érythémateux disséminé

Y Becker - 2022 - corpus.ulaval.ca
Résumé Mitochondria are intracellular organelles in control of numerous biological
functions (eg, from energy supply to steroidogenesis and programmed cell death by …