[HTML][HTML] Targeting oxidative stress as a therapeutic approach for idiopathic pulmonary fibrosis

C Estornut, J Milara, MA Bayarri, N Belhadj… - Frontiers in …, 2022 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial lung disease characterized by an
abnormal reepithelialisation, an excessive tissue remodelling and a progressive fibrosis …

[HTML][HTML] Natural products, alone or in combination with FDA-approved drugs, to treat COVID-19 and lung cancer

L Yang, Z Wang - Biomedicines, 2021 - mdpi.com
As a public health emergency of international concern, the highly contagious coronavirus
disease 2019 (COVID-19) pandemic has been identified as a severe threat to the lives of …

A comprehensive overview of Artemisinin and its derivatives as anticancer agents

Z Zeng, D Chen, L Chen, B He, Y Li - European Journal of Medicinal …, 2023 - Elsevier
Artemisinin is the crucial ingredient of artemisia annua, a traditional Chinese medicine used
for the therapy of malaria in China for hundreds of years. In recent years, the anticancer …

[HTML][HTML] The role of Nrf2 in pulmonary fibrosis: molecular mechanisms and treatment approaches

Y Wang, J Wei, H Deng, L Zheng, H Yang, X Lv - Antioxidants, 2022 - mdpi.com
Pulmonary fibrosis is a chronic, progressive, incurable interstitial lung disease with high
mortality after diagnosis and remains a global public health problem. Despite advances and …

[HTML][HTML] The mechanism and effect of autophagy, apoptosis, and pyroptosis on the progression of silicosis

S Tan, S Chen - International Journal of Molecular Sciences, 2021 - mdpi.com
Silicosis remains one of the most severe pulmonary fibrotic diseases worldwide, caused by
chronic exposure to silica dust. In this review, we have proposed that programmed cell death …

Pharmacologic Activities of Plant‐Derived Natural Products on Respiratory Diseases and Inflammations

D Timalsina, KP Pokhrel… - BioMed Research …, 2021 - Wiley Online Library
Respiratory inflammation is caused by an air‐mediated disease induced by polluted air,
smoke, bacteria, and viruses. The COVID‐19 pandemic is also a kind of respiratory disease …

Poria cocos polysaccharides attenuate chronic nonbacterial prostatitis by targeting the gut microbiota: Comparative study of Poria cocos polysaccharides and …

J Liu, L Liu, G Zhang, X Peng - International journal of biological …, 2021 - Elsevier
Finasteride is an antiandrogenic drug used for the clinical treatment of chronic nonbacterial
prostatitis (CNP). Recently, we reported the anti-CNP activity of Poria cocos polysaccharides …

[HTML][HTML] Tangeretin attenuates bleomycin-induced pulmonary fibrosis by inhibiting epithelial-mesenchymal transition via the PI3K/Akt pathway

J Li, Q Wei, K Song, Y Wang, Y Yang, M Li… - Frontiers in …, 2023 - frontiersin.org
Background: Pulmonary fibrosis (PF) is a terminal pathological change in a variety of lung
diseases characterized by excessive deposition of extracellular matrix, for which effective …

[HTML][HTML] Natural product-based potential therapeutic interventions of pulmonary fibrosis

M Hasan, NC Paul, SK Paul, ASM Saikat, H Akter… - Molecules, 2022 - mdpi.com
Pulmonary fibrosis (PF) is a disease-refractive lung condition with an increased rate of
mortality. The potential factors causing PF include viral infections, radiation exposure, and …

Mangostanin derivatives as novel and orally active phosphodiesterase 4 inhibitors for the treatment of idiopathic pulmonary fibrosis with improved safety

YY Huang, J Deng, YJ Tian, J Liang, X Xie… - Journal of Medicinal …, 2021 - ACS Publications
Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease, and its incidence rate is
rapidly rising. However, effective therapies for the treatment of IPF are still lacking …