Among gut microbiota-derived metabolites, trimethylamine-N-oxide (TMAO) is receiving
increased attention due to its possible role in the carcinogenesis of colorectal cancer (CRC) …

Cancer stem cells (CSCs) are the main culprits involved in therapy resistance and disease
recurrence in colorectal carcinoma (CRC). Results using cell culture, animal models and …

Mammalian cells use a specialized and complex machinery for the removal of altered
proteins or dysfunctional organelles. Such machinery is part of a mechanism called …

Ovarian cancer have a poor overall survival rate in patients, and late disease presentation
and chemoresistance are the main factors that lead to the mortality of ovarian cancer …

KIAA1429 is a major m6A methyltransferase, which plays important biological and
pharmacological roles in both human cancer or non-cancer diseases. KIAA1429 produce a …

Introduction. Liraglutide (L) is the analogue of human glucagon-like peptide 1 which
stimulates glucose-dependent insulin secretion and can modify the level of inflammatory …

We postulated that expression differences of autophagy-related genes are instrumental in
stratifying the risk of early relapse after surgery and evaluating the prognosis of patients with …

Colorectal tumorigenesis is a heterogeneous disease driven by multiple genetic and
epigenetic alterations. F-box and WD repeat domain containing 11 (FBXW11) is a member …

Our previous work suggested that high SIRT1 expression by cancer cells predicted a poor
colorectal cancer (CRC) prognosis, but its role in the tumor microenvironment was unclear …

Understanding molecular mechanisms of colorectal cancer (CRC) metastasis is urgently
required for targeted therapy and prognosis of metastatic CRC. In this study, we explored …