[HTML][HTML] Molecular mechanisms of ferroptosis and their involvement in brain diseases
I Costa, DJ Barbosa, S Benfeito, V Silva… - Pharmacology & …, 2023 - Elsevier
Ferroptosis is a type of regulated cell death characterized by intracellular accumulation of
iron and reactive oxygen species, inhibition of system Xc-, glutathione depletion …
iron and reactive oxygen species, inhibition of system Xc-, glutathione depletion …
[HTML][HTML] Autophagy mediates an amplification loop during ferroptosis
S Lee, N Hwang, BG Seok, S Lee, SJ Lee… - Cell Death & …, 2023 - nature.com
Ferroptosis, a programmed cell death, has been identified and associated with cancer and
various other diseases. Ferroptosis is defined as a reactive oxygen species (ROS) …
various other diseases. Ferroptosis is defined as a reactive oxygen species (ROS) …
[HTML][HTML] Edaravone ameliorates depressive and anxiety-like behaviors via Sirt1/Nrf2/HO-1/Gpx4 pathway
R Dang, M Wang, X Li, H Wang, L Liu, Q Wu… - Journal of …, 2022 - Springer
Background The inflammation and oxidative stress (OS) have been considered crucial
components of the pathogenesis of depression. Edaravone (EDA), a free radical scavenger …
components of the pathogenesis of depression. Edaravone (EDA), a free radical scavenger …
[HTML][HTML] Ferroptosis is essential for diabetic cardiomyopathy and is prevented by sulforaphane via AMPK/NRF2 pathways
X Wang, X Chen, W Zhou, H Men, T Bao, Y Sun… - … Pharmaceutica Sinica B, 2022 - Elsevier
Herein, we define the role of ferroptosis in the pathogenesis of diabetic cardiomyopathy
(DCM) by examining the expression of key regulators of ferroptosis in mice with DCM and a …
(DCM) by examining the expression of key regulators of ferroptosis in mice with DCM and a …
Melatonin suppresses ferroptosis induced by high glucose via activation of the Nrf2/HO‐1 signaling pathway in type 2 diabetic osteoporosis
H Ma, X Wang, W Zhang, H Li, W Zhao… - Oxidative medicine …, 2020 - Wiley Online Library
Ferroptosis is recently identified, an iron‐and reactive oxygen species‐(ROS‐) dependent
form of regulated cell death. This study was designed to determine the existence of …
form of regulated cell death. This study was designed to determine the existence of …
Ferroptosis and its potential role in the physiopathology of Parkinson's Disease
L Mahoney-Sánchez, H Bouchaoui, S Ayton… - Progress in …, 2021 - Elsevier
Parkinson's Disease (PD) is a common and progressive neurodegenerative disorder
characterised by motor impairments as well as non-motor symptoms. While dopamine …
characterised by motor impairments as well as non-motor symptoms. While dopamine …
[HTML][HTML] Resveratrol protects against myocardial ischemia-reperfusion injury via attenuating ferroptosis
T Li, Y Tan, S Ouyang, J He, L Liu - Gene, 2022 - Elsevier
Resveratrol (Res) is a polyphenol with a variety of biological activities. However, whether
Res can prevent myocardial ischemia–reperfusion (I/R) injury is not yet known. This study …
Res can prevent myocardial ischemia–reperfusion (I/R) injury is not yet known. This study …
[HTML][HTML] Progress in understanding the role of lncRNA in programmed cell death
N Jiang, X Zhang, X Gu, X Li, L Shang - Cell death discovery, 2021 - nature.com
Long non-coding RNAs (lncRNAs) are transcripts longer than 200 nucleotides but not
translated into proteins. LncRNAs regulate gene expressions at multiple levels, such as …
translated into proteins. LncRNAs regulate gene expressions at multiple levels, such as …
Dimethyl fumarate improves cognitive deficits in chronic cerebral hypoperfusion rats by alleviating inflammation, oxidative stress, and ferroptosis via NRF2/ARE/NF-κB …
N Yan, Z Xu, C Qu, JJ Zhang - International Immunopharmacology, 2021 - Elsevier
Cerebrovascular disease and its risk factors cause persistent decrease of cerebral blood
flow, chronic cerebral hypoperfusion (CCH) is the major foundation of vascular cognitive …
flow, chronic cerebral hypoperfusion (CCH) is the major foundation of vascular cognitive …
The lipid peroxidation product 4-hydroxynonenal inhibits NLRP3 inflammasome activation and macrophage pyroptosis
Pyroptosis is a form of cell death triggered by the innate immune system that has been
implicated in the pathogenesis of sepsis and acute lung injury. At the cellular level …
implicated in the pathogenesis of sepsis and acute lung injury. At the cellular level …