Alzheimer's disease (AD) is a devastating age-related neurodegenerative disorder with an
alarming increasing prevalence. Except for the recently FDA-approved Aducanumab of …

Obstructive sleep apnoea (OSA), characterized by chronic intermittent hypoxia (CIH), is
considered to be an independent risk for hypertension. The pathological cardiorespiratory …

Acetylcholine is produced in the spleen in response to vagus nerve activation; however, the
effects on antibody production have been largely unexplored. Here, we use a chronic vagus …

Inflammation and other immune responses are involved in the variety of diseases and
disorders. The acute response to endotoxemia includes activation of innate immune …

Production of inflammatory cytokines plays important roles in the response against tissue
injury and in host defense. Alterations in the production of inflammatory cytokines may cause …

Traumatic spinal cord injury (SCI) causes widespread damage to neurons, glia and
endothelia located throughout the spinal parenchyma. In response to the injury, resident and …

The aims of this review are to demonstrate that the changes in coagulation and fibrinolysis
observed in cardiac arrest and resuscitation can be recognized as disseminated …

Background Lipopolysaccharide (LPS)-induced systemic inflammation (SI) is associated
with neuroinflammation in the brain, hypotension, tachycardia, and multiple organs …

Background The carotid bodies and baroreceptors are sensors capable of detecting various
physiological parameters that signal to the brain via the afferent carotid sinus nerve for …

Canine parvovirus type II (CPV-2) infection induces canine parvoviral enteritis (CPE), which
in turn promotes sepsis and systemic inflammatory response syndrome (SIRS). Mortality in …