Organ-on-chip models for infectious disease research
Research on microbial pathogens has traditionally relied on animal and cell culture models
to mimic infection processes in the host. Over recent years, developments in microfluidics …
to mimic infection processes in the host. Over recent years, developments in microfluidics …
New treatment options for critically important WHO fungal priority pathogens
Background Yet often overlooked in public health discourse, fungal infections pose a
crucialglobal disease burden associated with annual mortality rates approximately equal to …
crucialglobal disease burden associated with annual mortality rates approximately equal to …
Inbred SJL mice recapitulate human resistance to Cryptococcus infection due to differential immune activation
MJ Davis, RE Martin, GM Pinheiro, ES Hoke, S Moyer… - Mbio, 2023 - Am Soc Microbiol
Cryptococcosis remains a significant threat to human health. While the popular C57BL/6J
mouse model of cryptococcosis has some advantages, there are some serious shortcomings …
mouse model of cryptococcosis has some advantages, there are some serious shortcomings …
[HTML][HTML] Connecting Cryptococcal Meningitis and Gut Microbiome
Fungal pathogens of the Cryptococcus neoformans species complex (C. neoformans SC)
are a major cause of fungal meningitis in immunocompromised individuals. As with other …
are a major cause of fungal meningitis in immunocompromised individuals. As with other …
[HTML][HTML] Impact factors of Blastocystis hominis infection in persons living with human immunodeficiency virus: a large-scale, multi-center observational study from …
SX Zhang, JC Wang, ZW Li, JX Zheng, WT Zhou… - Infectious Diseases of …, 2023 - Springer
Abstract Background Blastocystis hominis (Bh) is zoonotic parasitic pathogen with a high
prevalent globally, causing opportunistic infections and diarrhea disease. Human …
prevalent globally, causing opportunistic infections and diarrhea disease. Human …
Vaccine development for pathogenic fungi: current status and future directions
JL Chechi, FAC da Costa, JM Figueiredo… - Expert Review of …, 2023 - Taylor & Francis
Introduction Fungal infections are caused by a broad range of pathogenic fungi that are
found worldwide with different geographic distributions, incidences, and mortality rates …
found worldwide with different geographic distributions, incidences, and mortality rates …
[HTML][HTML] Fungicide-tolerant persister formation during cryptococcal pulmonary infection
W Ke, Y Xie, Y Chen, H Ding, L Ye, H Qiu, H Li… - Cell Host & Microbe, 2024 - cell.com
Bacterial persisters, a subpopulation of genetically susceptible cells that are normally
dormant and tolerant to bactericides, have been studied extensively because of their clinical …
dormant and tolerant to bactericides, have been studied extensively because of their clinical …
Aspartyl peptidase May1 induces host inflammatory response by altering cell wall composition in the fungal pathogen Cryptococcus neoformans
Cryptococcus neoformans causes cryptococcal meningoencephalitis, a disease that kills
more than 180,000 people annually. Contributing to its success as a fungal pathogen is its …
more than 180,000 people annually. Contributing to its success as a fungal pathogen is its …
Illuminating the Cryptococcus neoformans Species Complex: Unveiling Intracellular Structures with Fluorescent-Protein-Based Markers
R Shi, X Lin - Genetics, 2024 - academic.oup.com
Cryptococcus neoformans is a fungal pathogen of the top critical priority recognized by the
World Health Organization. This clinically important fungus also serves as a eukaryotic …
World Health Organization. This clinically important fungus also serves as a eukaryotic …
[HTML][HTML] Emerging trends of invasive yeast infections and azole resistance in Beijing intensive care units
J Yu, W Yang, X Fan, E Cui, R Min, H Yuan… - Journal of Hospital …, 2024 - Elsevier
Invasive fungal infections pose a substantial threat to patients in healthcare settings globally.
Recent changes in the prevalence of fungal species and challenges in conducting reference …
Recent changes in the prevalence of fungal species and challenges in conducting reference …