[HTML][HTML] Potential role of CXCL13/CXCR5 signaling in immune checkpoint inhibitor treatment in cancer
CH Hsieh, CZ Jian, LI Lin, GS Low, PY Ou, C Hsu… - Cancers, 2022 - mdpi.com
Simple Summary Immunotherapy is currently the backbone of new drug treatments for many
cancer patients. CXC chemokine ligand 13 (CXCL13) is an important factor involved in …
cancer patients. CXC chemokine ligand 13 (CXCL13) is an important factor involved in …
[HTML][HTML] Proteomics-based identification of dysregulated proteins in breast cancer
Immunohistochemistry (IHC) is still widely used as a morphology-based assay for in situ
analysis of target proteins as specific tumor antigens. However, as a very heterogeneous …
analysis of target proteins as specific tumor antigens. However, as a very heterogeneous …
Nanoplastics shape adaptive anticancer immunity in the colon in mice
The impact of nanoplastics (NPs) on human health is still not well understood, and more
research is needed to better understand the risks associated with these particles. In this …
research is needed to better understand the risks associated with these particles. In this …
Hepatocellular carcinomas, exhibiting intratumor fibrosis, express cancer-specific extracellular matrix remodeling and WNT/TGFB signatures, associated with poor …
Hepatocellular carcinomas, exhibiting intratumor fibrosis, e... : Hepatology Hepatocellular
carcinomas, exhibiting intratumor fibrosis, express cancer-specific extracellular matrix …
carcinomas, exhibiting intratumor fibrosis, express cancer-specific extracellular matrix …
System biology analysis to develop diagnostic biomarkers, monitoring pathological indexes, and novel therapeutic approaches for immune targeting based on maggot …
Early diagnosis and prognosis are prerequisites for mitigating mortality in gastric cancer
(GaCa). Identifying some causative or sensitive elements (coding RNA (cRNA)-non-cRNAs …
(GaCa). Identifying some causative or sensitive elements (coding RNA (cRNA)-non-cRNAs …
Identification of key genes associated with persistent immune changes and secondary immune activation responses induced by influenza vaccination after COVID-19 …
COVID-19 is hypothesized to exert enduring effects on the immune systems of patients,
leading to alterations in immune-related gene expression. This study aimed to scrutinize the …
leading to alterations in immune-related gene expression. This study aimed to scrutinize the …
[HTML][HTML] Investigating the Function of Human Jumping Translocation Breakpoint Protein (hJTB) and Its Interacting Partners through In-Solution Proteomics of MCF7 …
M Jayathirtha, D Whitham, S Alwine, M Donnelly… - Molecules, 2022 - mdpi.com
Human jumping translocation breakpoint (hJTB) gene is located on chromosome 1q21 and
is involved in unbalanced translocation in many types of cancer. JTB protein is ubiquitously …
is involved in unbalanced translocation in many types of cancer. JTB protein is ubiquitously …
[HTML][HTML] Different impacts of TP53 mutations on cell cycle-related gene expression among cancer types
K Sasaki, S Takahashi, K Ouchi, Y Otsuki… - Scientific Reports, 2023 - nature.com
Functional properties caused by TP53 mutations are involved in cancer development and
progression. Although most of the mutations lose normal p53 functions, some of them, gain …
progression. Although most of the mutations lose normal p53 functions, some of them, gain …
[HTML][HTML] Vascular endothelial profilin-1 drives a protumorigenic tumor microenvironment and tumor progression in renal cancer
Overexpression of actin-binding protein profilin-1 (Pfn1) correlates with advanced disease
features and adverse clinical outcome of patients with clear cell renal carcinoma, the most …
features and adverse clinical outcome of patients with clear cell renal carcinoma, the most …
[HTML][HTML] Chronic metabolic stress drives developmental programs and loss of tissue functions in non-transformed liver that mirror tumor states and stratify survival
CN Tzouanas, MS Sherman, JES Shay, AJ Rubin… - Biorxiv, 2023 - ncbi.nlm.nih.gov
Under chronic stress, cells must balance competing demands between cellular survival and
tissue function. In metabolic dysfunction-associated steatotic liver disease (MASLD, formerly …
tissue function. In metabolic dysfunction-associated steatotic liver disease (MASLD, formerly …